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[接受阿托品治疗的受试者外周血中的T淋巴细胞和B淋巴细胞]

[T and B lymphocytes in peripheral blood of subjects receiving atropine].

作者信息

Pluzańska A, Mazurowa A

出版信息

Acta Haematol Pol. 1977 Jan-Mar;8(1):39-43.

PMID:322435
Abstract

Using the rosette test E and EAC and determining presence of immunoglobulins on the surface of cells T and B lymphocyte counts were calculated in peripheral blood of 10 healthy subjects receiving atropine for some days. Parallely the activity of T cells was evaluated on the basis of blastic transformation degree after PHA stimulation. No differences were observed in the counts of T and B lymphocytes in peripheral blood before and during atropine administration. T lymphocytes showed, however, functional defects manifested with impairment of PHA-stimulated transformation.

摘要

采用玫瑰花结试验检测E和EAC,并测定T细胞和B细胞表面免疫球蛋白的存在情况,计算了10名连续数日接受阿托品治疗的健康受试者外周血中的T淋巴细胞和B淋巴细胞计数。同时,根据PHA刺激后细胞的增殖转化程度评估T细胞活性。在阿托品给药前和给药期间,外周血中T淋巴细胞和B淋巴细胞计数未观察到差异。然而,T淋巴细胞显示出功能缺陷,表现为PHA刺激的转化受损。

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