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[淋巴细胞增殖性疾病中的T淋巴细胞和B淋巴细胞]

[T- and B-lymphocytes in lymphoproliferative diseases].

作者信息

Tsveibakh A S, Gol'dman E I

出版信息

Vopr Onkol. 1978;24(1):11-6.

PMID:305684
Abstract

T-cell and B-cell markers and the response of lymphocytes to phytohemagglutinin (PHA) have been studied in 62 patients with chronic lymphocytic leukemia (CLL), in 3 patients with well-differentiated lymphocytic lymphoma and in 1 patient with lymphosarcoma. To investigate the functional integrity of T-lymphocytes in 10 patients with CLL the response of the T-cell-rich population to PHA was determined. The leukemic lymphocytes in all the cases but one had B-cell characteristic. The T-cell-rich population would show a normal response to PHA.

摘要

对62例慢性淋巴细胞白血病(CLL)患者、3例高分化淋巴细胞淋巴瘤患者和1例淋巴肉瘤患者的T细胞和B细胞标志物以及淋巴细胞对植物血凝素(PHA)的反应进行了研究。为了研究10例CLL患者T淋巴细胞的功能完整性,测定了富含T细胞群体对PHA的反应。除1例病例外,所有病例中的白血病淋巴细胞均具有B细胞特征。富含T细胞的群体对PHA表现出正常反应。

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