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幼年特发性关节炎:罗马儿童似乎比非罗马儿童面临更大的风险。

Juvenile Idiopathic Arthritis: Roma Children Seem to Run More Risk than Non-Roma.

机构信息

Department of Paediatric and Adolescent Medicine, Faculty of Medicine, P.J. Safarik University, Tr. SNP 1, 040 01 Kosice, Slovakia.

Graduate School Kosice Institute for Society and Health, Faculty of Medicine, P.J. Safarik University, Tr. SNP 1, 040 01 Kosice, Slovakia.

出版信息

Int J Environ Res Public Health. 2020 Mar 31;17(7):2377. doi: 10.3390/ijerph17072377.

DOI:10.3390/ijerph17072377
PMID:32244474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7177970/
Abstract

Ethnic information regarding juvenile idiopathic arthritis (JIA) exists for various populations across the world but is fully lacking for Roma. We assessed the occurrence and clinical characteristics of JIA in Roma vs. non-Roma children. : We obtained data on all outpatients ( = 142) from a paediatric rheumatology centre (age 3 to 18 years) in the eastern part of Slovakia (Kosice region). We assessed patients' age, gender, disease type and related extra-articular conditions by ethnicity. We obtained population data from the 2011 census. : The share of Roma children was higher in the clinical JIA sample than in the overall population (24.6%, = 35, Roma in the sample vs. 10.8%, = 142, Roma in the population, < 0.05). Moreover, Roma children had been diagnosed more frequently with extra-articular conditions but did not differ in other symptoms. Treatments also did not differ by ethnicity. : Roma children had been diagnosed more with JIA than their non-Roma peers. This calls for further research on the causes of this increased disease burden in Roma children.

摘要

种族信息在世界范围内存在于各种人群中的青少年特发性关节炎(JIA),但在罗姆人(吉普赛人)中完全缺失。我们评估了罗姆人和非罗姆人儿童中 JIA 的发生和临床特征。我们从斯洛伐克东部(科希策地区)的一家儿科风湿病中心(年龄 3 至 18 岁)获得了所有门诊患者(= 142)的数据。我们按种族评估了患者的年龄、性别、疾病类型和相关的关节外情况。我们从 2011 年的人口普查中获得了人口数据。罗姆儿童在临床 JIA 样本中的比例高于总人口(24.6%,= 35,样本中的罗姆人 vs. 10.8%,= 142,总人口中的罗姆人,< 0.05)。此外,罗姆儿童被诊断出关节外疾病的频率更高,但其他症状没有差异。治疗方法也不受种族影响。罗姆儿童被诊断出 JIA 的比例高于非罗姆儿童。这需要进一步研究罗姆儿童疾病负担增加的原因。

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Int J Public Health. 2019 Sep;64(7):1117-1121. doi: 10.1007/s00038-019-01246-9. Epub 2019 May 21.
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Lessons learned from twins in autoimmune and chronic inflammatory diseases.从自身免疫和慢性炎症性疾病的双胞胎中吸取的经验教训。
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BMC Public Health. 2017 Jan 28;17(1):128. doi: 10.1186/s12889-017-4029-x.
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