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颅骨骨折对钝性冲击致创伤性脑损伤风险的影响。

Influence of Skull Fracture on Traumatic Brain Injury Risk Induced by Blunt Impact.

机构信息

State Key Laboratory of Vehicle NVH and Safety Technology, China Automotive Engineering Reasearch Institute Co., Ltd. and Chongqing Chang'An Automobile Co., Ltd., Chongqing 401122, China.

Key Laboratory of Advanced Manufacturing Technology for Automobile Parts, Ministry of Education, Chongqing University of Technology, Chongqing 400054, China.

出版信息

Int J Environ Res Public Health. 2020 Apr 1;17(7):2392. doi: 10.3390/ijerph17072392.

DOI:10.3390/ijerph17072392
PMID:32244585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7177884/
Abstract

This study is aimed at investigating the influence of skull fractures on traumatic brain injury induced by blunt impact via numerous studies of head-ground impacts. First, finite element (FE) damage modeling was implemented in the skull of the Total HUman Model for Safety (THUMS), and the skull fracture prediction performance was validated against a head-ground impact experiment. Then, the original head model of the THUMS was assigned as the control model without skull element damage modeling. Eighteen (18) head-ground impact models were established using these two FE head models, with three head impact locations (frontal, parietal, and occipital regions) and three impact velocities (25, 35, and 45 km/h). The predicted maximum principal strain and cumulative strain damage measure of the brain tissue were employed to evaluate the effect of skull fracture on the cerebral contusion and diffuse brain injury risks, respectively. Simulation results showed that the skull fracture could reduce the risk of diffuse brain injury risk under medium and high velocities significantly, while it could increase the risk of brain contusion under high-impact velocity.

摘要

本研究旨在通过大量头部撞击地面的研究，探讨颅骨骨折对钝性冲击引起的创伤性脑损伤的影响。首先，在 Total HUman Model for Safety（THUMS）的颅骨中进行了有限元（FE）损伤建模，并对头撞击地面的实验进行了颅骨骨折预测性能验证。然后，将 THUMS 的原始头部模型指定为没有颅骨元素损伤建模的对照模型。使用这两个 FE 头部模型建立了 18 个头部撞击地面模型，分别有三个头部撞击位置（额部、顶骨部和枕部）和三个撞击速度（25、35 和 45km/h）。采用预测的脑组织最大主应变和累积应变损伤量来评估颅骨骨折对脑挫裂伤和弥漫性脑损伤风险的影响。模拟结果表明，颅骨骨折可显著降低中高速时弥漫性脑损伤风险，而在高速撞击时则会增加脑挫裂伤的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/38483499c5cb/ijerph-17-02392-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/dc8d2b3acee0/ijerph-17-02392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/eb120a4bd3c7/ijerph-17-02392-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/474ecfb93f8d/ijerph-17-02392-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/18479c071e0e/ijerph-17-02392-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/d7c48a3e8933/ijerph-17-02392-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/93915b80ee40/ijerph-17-02392-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/f7943f460ba7/ijerph-17-02392-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/45c5ca841e4d/ijerph-17-02392-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/e13f1e674d50/ijerph-17-02392-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/f652ca9a7431/ijerph-17-02392-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/24100464c4ab/ijerph-17-02392-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/2eab24d70109/ijerph-17-02392-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/6934f71f8714/ijerph-17-02392-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/38483499c5cb/ijerph-17-02392-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/dc8d2b3acee0/ijerph-17-02392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/eb120a4bd3c7/ijerph-17-02392-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/474ecfb93f8d/ijerph-17-02392-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/18479c071e0e/ijerph-17-02392-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/d7c48a3e8933/ijerph-17-02392-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/93915b80ee40/ijerph-17-02392-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/f7943f460ba7/ijerph-17-02392-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/45c5ca841e4d/ijerph-17-02392-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/e13f1e674d50/ijerph-17-02392-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/f652ca9a7431/ijerph-17-02392-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/24100464c4ab/ijerph-17-02392-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/2eab24d70109/ijerph-17-02392-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/6934f71f8714/ijerph-17-02392-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc1/7177884/38483499c5cb/ijerph-17-02392-g014.jpg

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