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脱敏疗法成功治疗胰岛素过敏:一例报告及文献综述

Successful Treatment of Insulin Allergy with Desensitization Therapy: A Case Report and Literature Review.

作者信息

Elfekih Hamza, Hadjkacem Faten, Elleuch Mouna, Ghorbel Dorra, Charfi Nadia, Mnif Fatma, Rekik Nabila, Mnif Mouna, Abid Mohamed

机构信息

Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia.

出版信息

Iran J Allergy Asthma Immunol. 2019 Oct 23;18(5):572-583. doi: 10.18502/ijaai.v18i5.1927.

DOI:10.18502/ijaai.v18i5.1927
PMID:32245301
Abstract

Insulin therapy is an essential treatment for type 1 and uncontrolled type 2 diabetes mellitus (DM). Hypersensitivity reactions have been described since the first administration of insulin, the same as any other therapy. Despite being a rare situation nowadays, it requires careful intra-hospital monitoring and multidisciplinary management. Here, we present a case of a 57-year-old patient with type 2 DM, an average glycemic control, and both penicillin and insulin allergy. Heunderwent a desensitization protocol which allowed successfully dismiss him with intermediate-acting insulin.

摘要

胰岛素治疗是1型糖尿病和未控制的2型糖尿病(DM)的重要治疗方法。自首次使用胰岛素以来,就像任何其他治疗一样,已出现过敏反应的描述。尽管如今这种情况很少见,但仍需要在医院内进行仔细监测和多学科管理。在此,我们报告一例57岁的2型糖尿病患者,其血糖控制一般,同时对青霉素和胰岛素过敏。他接受了脱敏方案,最终成功停用了中效胰岛素。

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Successful Treatment of Insulin Allergy with Desensitization Therapy: A Case Report and Literature Review.脱敏疗法成功治疗胰岛素过敏:一例报告及文献综述
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引用本文的文献

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Clinical Outcomes and Complications of Basal, Bolus, and Combination Insulin Regimens in Type 2 Diabetes Mellitus: Evidence from Published Case Reports.2型糖尿病患者基础胰岛素、餐时胰岛素及联合胰岛素治疗方案的临床结局与并发症:来自已发表病例报告的证据
Diabetes Metab Syndr Obes. 2025 Sep 3;18:3215-3236. doi: 10.2147/DMSO.S545571. eCollection 2025.
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Nursing a patient with latent autoimmune diabetes in adults with insulin-related lipodystrophy, allergy, and exogenous insulin autoimmune syndrome: A case report.
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World J Clin Cases. 2022 Jul 16;10(20):7163-7170. doi: 10.12998/wjcc.v10.i20.7163.