Manning D J, Bowden P J, Hathorn M K, Stothers J K
Dept. of Physiology, London Hospital Medical College, Whitechapel, U.K.
Early Hum Dev. 1988 Dec;18(2-3):175-84. doi: 10.1016/0378-3782(88)90054-0.
Oesophageal pressure and ventilation were recorded during sleep in healthy full-term neonates with sleep state defined by one of two methods; in 35 infants by combined behavioural and electroencephalographic criteria, and in a further 13 infants by behavioural criteria alone. Spontaneous oesophageal contractions occurred in all infants during active sleep but rarely during quiet sleep. The transition from active to quiet sleep was accompanied by a gradual reduction in the frequency of these contractions. Oesophageal contractions associated with sighs and contractions shortly following interruption of breathing suggestive of swallowing were also significantly more common in active sleep. In 13 infants who showed periodic breathing the same differences in prevalence of spontaneous oesophageal contractions in each sleep state were observed.
在健康足月儿睡眠期间记录食管压力和通气情况，睡眠状态通过两种方法之一来定义；35名婴儿采用行为和脑电图联合标准，另有13名婴儿仅采用行为标准。所有婴儿在主动睡眠期间均出现自发性食管收缩，但在安静睡眠期间很少出现。从主动睡眠向安静睡眠的转变伴随着这些收缩频率的逐渐降低。与叹息相关的食管收缩以及呼吸中断后不久提示吞咽的收缩在主动睡眠中也明显更为常见。在13名出现周期性呼吸的婴儿中，在每种睡眠状态下自发性食管收缩的发生率也存在同样的差异。
