Christensen P B
Department of Neurology, Aalborg Hospital, Denmark.
Eur Neurol. 1988;28(5):285-7. doi: 10.1159/000116285.
Two elderly siblings with myotonic dystrophy (MD) were admitted with symptoms and signs of normal pressure hydrocephalus, the diagnosis being confirmed by CT scan and infusion test. A further 11 younger members of the family also had MD; in 2 of these, none of whom had cerebral symptoms, CT scan showed cerebral ventricular enlargement. Based on these findings, together with earlier reports on progressive cerebral ventricular enlargement in patients with MD, it is suggested that in some cases normal pressure hydrocephalus may be a late complication of MD.
两名患有强直性肌营养不良（MD）的老年兄弟姐妹因正常压力脑积水的症状和体征入院，CT扫描和灌注试验证实了诊断。该家族另外11名较年轻成员也患有MD；其中2人没有脑部症状，但CT扫描显示脑室扩大。基于这些发现，再结合此前关于MD患者进行性脑室扩大的报道，提示在某些情况下，正常压力脑积水可能是MD的晚期并发症。
