弥散张量成像显示急性儿科脑震荡中水扩散参数的改变。
The diffusion-tensor imaging reveals alterations in water diffusion parameters in acute pediatric concussion.
机构信息
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma, 22, Bol'shaya Polyanka St., Moscow, 119180, Russia.
N.M. Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, 4, Kosygina St., Moscow, 119334, Russia.
出版信息
Acta Neurol Belg. 2021 Dec;121(6):1463-1468. doi: 10.1007/s13760-020-01347-w. Epub 2020 Apr 3.
Wide-spread visualization methods which are computed tomography (CT) and magnetic resonance imaging (MRI) are not sensitive to mild traumatic brain injury (mTBI). However, mTBI may cause changes of cerebral microstructure that could be found using diffusion-tensor imaging. The aim of this study is to reveal the impact of acute mTBI (no more than 3 days after trauma) on diffusion parameters in corpus callosum, corticospinal tract, and thalamus in children (aged 14-18). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were analyzed. Significant increase in FA and decrease in ADC were observed in thalamus. The trend to an increase in FA is observed in corpus callosum.
广泛使用的计算机断层扫描（CT）和磁共振成像（MRI）等可视化方法对轻度创伤性脑损伤（mTBI）并不敏感。然而，mTBI 可能导致脑微结构的变化，这些变化可以通过弥散张量成像发现。本研究旨在揭示急性 mTBI（创伤后不超过 3 天）对儿童（14-18 岁）胼胝体、皮质脊髓束和丘脑的弥散参数的影响。分析了各向异性分数（FA）和表观扩散系数（ADC）。在丘脑观察到 FA 显著增加和 ADC 显著降低。在胼胝体中观察到 FA 增加的趋势。
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