Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Asian Pac J Allergy Immunol. 2022 Sep;40(3):254-262. doi: 10.12932/AP-100120-0738.
Pruritus is commonly associated with skin disorders. The 5-D itch scale was developed as a specific questionnaire for pruritus.
This study aimed to evaluate the validity, reliability, and sensitivity to change of the Thai 5-D itch scale in Thai patients.
The Thai Dermatology Life Quality Index (DLQI), patient's global assessment of disease severity (PatGA-VAS), Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL), and seven-day urticaria activity score (UAS7) were evaluated as correlation with Thai 5-D itch scale. Seventy-five stable patients (42 chronic urticaria patients and 33 eczema patients), who had no change in disease severity after 4-weeks were assessed for test-retest reliability.
Of 130 pruritus patients who were treated at Department of Dermatology, Siriraj Hospital, 65 patients were diagnosed with chronic urticaria. The others were diagnosed with eczema. The validity of Thai 5-D itch scale correlated strongly with Thai DLQI total score (r = 0.76, p < 0.0001) and PatGA-VAS (r = 0.79, p < 0.0001). The strong reliability of Thai 5-D itch scale was demonstrated as intraclass correlation coefficient of 0.90. The changes in Thai 5-D itch scale was correlated with the changes in PatGA-VAS and UAS7 which indicated that the Thai 5-D itch scale had good sensitivity to change (r = 0.66) and (r = 0.67), respectively.
The Thai 5-D itch scale is a questionnaire with good validity, reliability and sensitivity to change to evaluate pruritus in Thai patients. This will support the use of 5-D itch scale in practice, in other languages.
瘙痒通常与皮肤疾病有关。5-D 瘙痒量表是专门为瘙痒而开发的特定问卷。
本研究旨在评估泰国 5-D 瘙痒量表在泰国患者中的有效性、可靠性和对变化的敏感性。
评估泰国皮肤病生活质量指数（DLQI）、患者疾病严重程度总体评估（PatGA-VAS）、慢性荨麻疹生活质量问卷（CU-Q2oL）和 7 天荨麻疹活动评分（UAS7）与泰国 5-D 瘙痒量表的相关性。对 75 例病情稳定（42 例慢性荨麻疹患者和 33 例湿疹患者）且 4 周后病情无变化的患者进行测试-重测信度评估。
在接受皮肤科治疗的 130 例瘙痒患者中，65 例被诊断为慢性荨麻疹，其余患者被诊断为湿疹。泰国 5-D 瘙痒量表的有效性与泰国 DLQI 总分（r = 0.76，p < 0.0001）和 PatGA-VAS（r = 0.79，p < 0.0001）高度相关。泰国 5-D 瘙痒量表具有很强的可靠性，其组内相关系数为 0.90。泰国 5-D 瘙痒量表的变化与 PatGA-VAS 和 UAS7 的变化相关，表明该量表对变化具有良好的敏感性（r = 0.66）和（r = 0.67）。
泰国 5-D 瘙痒量表是一种具有良好有效性、可靠性和对变化敏感性的问卷，可用于评估泰国患者的瘙痒。这将支持在实践中使用 5-D 瘙痒量表，以及在其他语言环境下使用。
