Löw O
Friedrich-Schiller-University Jena, Institute for Pathological Anatomy.
Gegenbaurs Morphol Jahrb. 1988;134(5):685-92.
A series of longitudinally cut step sections with a distance of 50 microns of a rabbit thyroid gland was measured by point counting for the relative tissue elements colloid, epithelium, and interstitium. Furthermore, the ratio epithelium:colloid was computed, which was somewhat high, indicating an activated stage. Higher colloid data were found in the outer regions and insignificantly lower epithelium values. Neither the volume data nor the distribution of the structure elements show any difference between both of the lobes. The degree of heterogeneity was comparably low, but only about 30% of all data for the relative colloid percentages or for the ratios are enclosed in a range of +/- 5% in relation to the most accurate value from all hits all over the gland, and about 20% of the ratio data are crossing the +/- 20% borderlines. It was calculated that measuring of not more than 5 sections with approximately equal distances with a very few 10(3) hits yields values of an acceptable accuracy for all parameters and this with a reasonable time expense.
对一只兔子甲状腺的一系列纵向切割的步长为50微米的切片进行点计数，以测量胶体、上皮和间质等相对组织成分。此外，计算上皮:胶体的比率，该比率略高，表明处于激活阶段。在外部区域发现较高的胶体数据，上皮值略低。两个叶之间的体积数据和结构元素分布均无差异。异质性程度相对较低，但相对于整个腺体所有测量点的最准确值，相对胶体百分比或比率的所有数据中只有约30%落在±5%的范围内，约20%的比率数据跨越了±20%的边界。经计算，测量不超过5个距离大致相等的切片，只需进行很少的10³次计数，就能得到所有参数的可接受精度的值，且时间成本合理。
