Löw O
Exp Pathol. 1982;22(1):43-58.
The colloid and epithelium percentages in the thyroid gland are characterized by a noticeable variability and a zonal heterogeneity; in the border region an enriching of the colloid component is observed and in the central part a higher epithelium concentration. Studies with different net point distances and measuring areas led to the following conclusions: provided that a sufficient number of points are attached, a distance of 250 micrometers may be used for common tests; the prolongation of the measuring time for lower distances than 100 micrometers is often not accompanied by an essentially better accuracy. Measuring areas should not be too small, even between fields of 20 mm2 differences of the few per cents may be observed in the same slide. The polynomial regression curve for the comparison of epithelium and colloid data seems to be influenced by the interstitium values: up to about 30% colloid an increase of the epithelium values is seen, since a further growing of the colloid percentages is connected with a decline of the epithelium percentages.
甲状腺中胶体和上皮细胞的百分比具有明显的变异性和区域异质性；在边界区域观察到胶体成分增加，而在中心部分上皮细胞浓度较高。对不同网点距离和测量面积的研究得出以下结论：如果附着足够数量的点，则250微米的距离可用于常规测试；测量距离小于100微米时延长测量时间通常不会带来本质上更好的准确性。测量面积不应太小，即使在20平方毫米的区域之间，同一张载玻片上也可能观察到百分之几的差异。用于比较上皮细胞和胶体数据的多项式回归曲线似乎受间质值的影响：胶体含量高达约30%时，上皮细胞值会增加，因为胶体百分比的进一步增加与上皮细胞百分比的下降有关。
