Botanical Institute and Cluster of Excellence on Plant Sciences (CEPLAS), Biocenter, University of Cologne, 50674 Cologne, Germany.
Physiol Plant. 2020 Jul;169(3):418-429. doi: 10.1111/ppl.13103. Epub 2020 Apr 30.
Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC1/SUPPRESSOR OF PHYA-105 (COP1/SPA) is an E3 ubiquitin ligase complex that prevents photomorphogenesis in darkness by ubiquitinating and subsequently degrading light-responsive transcription factors. Upon light perception, photoreceptors directly interact with the COP1/SPA complex to suppress its activity. In blue light (450-500 nm of visible spectrum), COP1/SPA activity is inhibited by the cryptochrome photoreceptors (CRY1 and CRY2), FKF1 from the ZEITLUPE family as well as phytochrome A. Together, these photoreceptors regulate vital aspects of plant growth and development from seedling stage to the induction of flowering. This review presents and discusses the recent advances in blue light-mediated suppression of COP1/SPA activity.
拟南芥组成型光形态建成 1/光敏色素 A 抑制因子 105 (COP1/SPA) 是一种 E3 泛素连接酶复合物，通过泛素化和随后降解光响应转录因子来防止黑暗中的光形态建成。在光感知后，光受体直接与 COP1/SPA 复合物相互作用以抑制其活性。在蓝光（可见光谱的 450-500nm）中，COP1/SPA 活性被隐花色素受体（CRY1 和 CRY2）、ZEITLUPE 家族的 FKF1 和光敏色素 A 抑制。这些光受体共同调节植物生长和发育的重要方面，从幼苗阶段到开花的诱导。本综述介绍和讨论了蓝光介导的 COP1/SPA 活性抑制的最新进展。
