Ponnu Jathish, Hoecker Ute
Institute for Plant Sciences and Cluster of Excellence on Plant Sciences (CEPLAS), Biocenter, University of Cologne, Cologne, Germany.
Front Plant Sci. 2022 Feb 28;13:844714. doi: 10.3389/fpls.2022.844714. eCollection 2022.
Cryptochromes (CRYs) are blue light photoreceptors that regulate growth, development, and metabolism in plants. In (Arabidopsis), CRY1 and CRY2 possess partially redundant and overlapping functions. Upon exposure to blue light, the monomeric inactive CRYs undergo phosphorylation and oligomerization, which are crucial to CRY function. Both the N- and C-terminal domains of CRYs participate in light-induced interaction with multiple signaling proteins. These include the COP1/SPA E3 ubiquitin ligase, several transcription factors, hormone signaling intermediates and proteins involved in chromatin-remodeling and RNA N6 adenosine methylation. In this review, we discuss the mechanisms of Arabidopsis CRY signaling in photomorphogenesis and the recent breakthroughs in Arabidopsis CRY research.
隐花色素（CRYs）是蓝光光感受器，可调节植物的生长、发育和新陈代谢。在拟南芥中，CRY1和CRY2具有部分冗余和重叠的功能。暴露于蓝光下时，单体无活性的CRYs会发生磷酸化和寡聚化，这对CRY功能至关重要。CRYs的N端和C端结构域均参与与多种信号蛋白的光诱导相互作用。这些蛋白包括COP1/SPA E3泛素连接酶、几种转录因子、激素信号中间体以及参与染色质重塑和RNA N6腺苷甲基化的蛋白质。在本综述中，我们讨论了拟南芥CRY信号在光形态建成中的机制以及拟南芥CRY研究的最新突破。
