Université de Paris, ITODYS, CNRS, UMR 7086, 15 Rue J-A de Baïf, F-75013, Paris, France.
Department of Advanced Materials Science and Nanotechnology (AMSN), University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Nghĩa Đô, Cầu Giấy, Hanoi, Viet Nam.
Biosens Bioelectron. 2020 Jun 1;157:112166. doi: 10.1016/j.bios.2020.112166. Epub 2020 Mar 25.
Among organic thin film transistors (OTFTs), Organic Electrochemical Transistors (OECTs) have been extensively used for cell monitoring while Electrolyte-Gated Organic Field-Effect Transistors (EGOFETs) have never been described for that kind of application. However, EGOFETs are well adapted for this use because, as well as OECTs, they can operate directly in aqueous solutions such as cells culture media, but they offer much a higher on/off ratio which could lead to better sensitivity. As a proof of concept, we propose herein to monitor the photosynthetic activity of a cyanobacterium (Anabaena flos-aquae) contained within an EGOFET's electrolyte.
在有机薄膜晶体管 (OTFT) 中，有机电化学晶体管 (OECT) 已被广泛用于细胞监测，而电解质门控有机场效应晶体管 (EGOFET) 从未被描述用于此类应用。然而，EGOFET 非常适合这种用途，因为与 OECT 一样，它们可以直接在水基溶液（如细胞培养基）中工作，但它们提供了更高的开关比，这可能会导致更高的灵敏度。作为概念验证，我们在此提出在 EGOFET 的电解质中监测蓝藻（鱼腥藻）的光合作用活性。
