Collares Fabrício M, Garcia Isadora M, Klein Mariana, Parolo Clarissa F, Sánchez Felipe Antonio L, Takimi Antônio, Bergmann Carlos P, Samuel Susana Maria W, Melo Mary Anne, Leitune Vicente Cb
Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre 90035-003, RS, Brazil.
Biochemistry and Microbiology Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre 90035-003, RS, Brazil.
Polymers (Basel). 2020 Apr 2;12(4):789. doi: 10.3390/polym12040789.
This study aimed to evaluate the effect of needle-like zinc oxide nanostructures (ZnO-NN) on the physical, chemical, and antibacterial properties of experimental methacrylate-based dental sealers. ZnO-NN was synthesized and characterized. ZnO-NN was added to a co-monomer blend at 20, 30, and 40 wt.%. One group without ZnO-NN was used as a control. The dental resin sealers were evaluated for their flow, film thickness, water sorption, solubility, radiopacity, degree of conversion (DC), dental-sealer interface characterization via micro-Raman, and antibacterial activity. ZnO-NN presented a mean needle diameter of 40 nm and 16 m/g of surface area. There was no difference among groups containing ZnO-NN regarding their flow. The ZnO-NN addition significantly increased the film thickness. Water sorption and solubility tests showed no difference among groups. The radiopacity increased, and DC decreased with higher concentrations of ZnO-NN. Micro-Raman suggested that ZnO-NN was in close contact with root canal dentin. Overall, the incorporation of ZnO-NN provided an antibacterial effect against without a significant detrimental impact on the physical and chemical functionality of the material. The use of ZnO-NN as an inorganic filler is a potential application within dental materials intended for root canal treatment.
本研究旨在评估针状氧化锌纳米结构（ZnO-NN）对实验性甲基丙烯酸酯基牙科密封剂的物理、化学和抗菌性能的影响。合成并表征了ZnO-NN。将ZnO-NN以20%、30%和40%的重量百分比添加到共聚单体共混物中。一组不添加ZnO-NN作为对照。对牙科树脂密封剂的流动性、膜厚度、吸水性、溶解性、射线不透性、转化率（DC）、通过显微拉曼光谱对牙科密封剂界面进行表征以及抗菌活性进行了评估。ZnO-NN的平均针直径为40nm，表面积为16m²/g。含ZnO-NN的各组之间在流动性方面没有差异。添加ZnO-NN显著增加了膜厚度。吸水性和溶解性测试表明各组之间没有差异。随着ZnO-NN浓度的增加，射线不透性增加，而DC降低。显微拉曼光谱表明ZnO-NN与根管牙本质紧密接触。总体而言，加入ZnO-NN对变形链球菌具有抗菌作用，且对材料的物理和化学功能没有显著的不利影响。将ZnO-NN用作无机填料是根管治疗用牙科材料中的一种潜在应用。
