锌钙纳米复合材料及其抗菌性能研究。

A Study of Zn-Ca Nanocomposites and Their Antibacterial Properties.

机构信息

Laboratorio de Investigación en Nanomateriales, Agua y Energía, Departamento de Ingeniería, Centro Universitario de los Altos, Universidad de Guadalajara, Av. Rafael Casillas Aceves 1200, Tepatitlán de Morelos 47600, Mexico.

Especialidad en Odontopediatría, Centro Universitario de los Altos, Universidad de Guadalajara, Av. Rafael Casillas Aceves 1200, Tepatitlán de Morelos 47600, Mexico.

出版信息

Int J Mol Sci. 2022 Jun 29;23(13):7258. doi: 10.3390/ijms23137258.

This study aimed to develop Ca doped ZnO nanoparticles (NPs) and investigate their antibacterial properties against microorganisms of dental interest. Zn-Ca NPs were synthesized by the sol-gel method with different concentrations of Ca (1, 3, and 5 wt. %) and subsequently characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-vis spectroscopy and Fourier transform infrared spectroscopy (FT-IR). The Kirby-Bauer method was used to measure antibacterial effects. NPs showed the wurzite phase of ZnO and bandgap energies (Eg) from 2.99 to 3.04 eV. SEM analysis showed an average particle size of 80 to 160 nm. The treatments that presented the best antibacterial activity were Zn-Ca 3% and Zn-Ca 5%. ZnO NPs represent an alternative to generate and improve materials with antibacterial capacity for dental applications.

本研究旨在制备 Ca 掺杂 ZnO 纳米粒子（NPs），并研究其对口腔相关微生物的抗菌性能。采用溶胶-凝胶法制备 Zn-Ca NPs，通过不同浓度的 Ca（1、3 和 5wt.%）进行掺杂，并通过扫描电子显微镜（SEM）、X 射线衍射（XRD）、紫外-可见分光光度计和傅里叶变换红外光谱（FT-IR）进行表征。采用 Kirby-Bauer 法测定抗菌效果。结果表明，NPs 具有 ZnO 的纤锌矿相和 2.99 至 3.04 eV 的能带隙能量（Eg）。SEM 分析显示平均粒径为 80 至 160nm。具有最佳抗菌活性的处理方法是 Zn-Ca 3%和 Zn-Ca 5%。ZnO NPs 为口腔应用中生成和改善具有抗菌能力的材料提供了一种替代方法。