Medecins Sans Frontieres, Khayelitsha, South Africa.
Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa; Department of Infectious Diseases, Imperial College London, United Kingdom.
Paediatr Respir Rev. 2020 Nov;36:44-51. doi: 10.1016/j.prrv.2020.02.004. Epub 2020 Mar 5.
It is estimated that 20 million children are exposed to tuberculosis (TB) each year, making TB a global paediatric health emergency. TB preventative efforts have long been overlooked. With the view of achieving "TB elimination" in "our lifetime", this paper explores challenges and potential solutions in the TB prevention cascade, including identifying children who have been exposed to TB; detecting TB infection in these children; identifying those at highest risk of progressing to disease; implementing treatment of TB infection; and mobilizing multiple stakeholders support to successfully prevent TB.
据估计，每年有 2000 万儿童接触结核病（TB），使结核病成为全球儿科健康紧急情况。长期以来，结核病预防工作一直被忽视。为了在“有生之年”实现“结核病消除”，本文探讨了结核病预防环节中面临的挑战和潜在解决方案，包括发现接触过结核病的儿童；在这些儿童中检测结核病感染；确定哪些儿童具有发展为疾病的最高风险；实施结核病感染治疗；以及动员多方利益相关者支持，以成功预防结核病。
