Clinical and Toxicological Analyzes Department, Faculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Adv Exp Med Biol. 2021;1307:115-128. doi: 10.1007/5584_2020_513.
Diabetes mellitus (DM) is a metabolic disorder characterised by hyperglycemia and abnormalities in carbohydrate, fat and protein metabolism. Several studies demonstrated that foods typical of the Mediterranean diet (MedDiet), including vegetables, fruits, oilseeds, extra virgin olive oil and fish, can promote health benefits for individuals at risk of or with type 2 diabetes (T2DM). In this review, we summarised randomised clinical trials, cohort studies, meta-analyses and systematic reviews that evaluated the effects of the MedDiet on metabolic control of T2DM. The data suggest that the MedDiet influences cardiovascular risk factors, including blood pressure, lipid profile, insulin resistance, inflammation and glucose metabolism, in T2DM patients. In conclusion, the MedDiet appears to protect patients from macro- and microangiopathy and should be considering in the management of diabetic patients.
糖尿病(DM)是一种代谢紊乱,其特征为高血糖和碳水化合物、脂肪和蛋白质代谢异常。多项研究表明,地中海饮食(MedDiet)中的典型食物,包括蔬菜、水果、油籽、特级初榨橄榄油和鱼,可促进处于 2 型糖尿病(T2DM)风险中或患有 2 型糖尿病的个体的健康获益。在这篇综述中,我们总结了评估 MedDiet 对 T2DM 代谢控制影响的随机临床试验、队列研究、荟萃分析和系统评价。数据表明,MedDiet 影响 T2DM 患者的心血管危险因素,包括血压、血脂谱、胰岛素抵抗、炎症和葡萄糖代谢。总之,MedDiet 似乎可保护患者免受大血管和微血管病变的影响,应该在糖尿病患者的管理中考虑。