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lockdown 限制措施遏制了 2019 年新型冠状病毒病在中国黄石市的传播:早期流行病学调查结果。

Lockdown Contained the Spread of 2019 Novel Coronavirus Disease in Huangshi City, China: Early Epidemiological Findings.

机构信息

Department of Internal Medicine, Huangshi Youse Hospital affiliated to College of Arts & Science of Jianghan University, Huangshi, China.

Huangshi Center for Disease Control and Prevention, Huangshi, China.

出版信息

Clin Infect Dis. 2020 Sep 12;71(6):1454-1460. doi: 10.1093/cid/ciaa390.

Abstract

BACKGROUND

To control the spread of 2019 novel coronavirus disease (COVID-19), China sealed Wuhan on 23 January 2020 and soon expanded lockdown to 12 other cities in Hubei province. We aimed to describe the epidemiological characteristics in one of the cities and highlight the effect of current implemented lockdown and nonpharmaceutical interventions.

METHODS

We retrieved data of reported cases in Huangshi and Wuhan from publicly available disease databases. Local epidemiological data on suspected or confirmed cases in Huangshi were collected through field investigation. Epidemic curves were constructed with data on reported and observed cases.

RESULTS

The accumulated confirmed COVID-19 cases and fatality in Huangshi were reported to be 1015 and 3.74%, respectively, compared with 50006 and 5.08% in Wuhan until 27 March 2020. Right after 24 January, the epidemic curve based on observed cases in Huangshi became flattened. And 1 February 2020 was identified as the "turning point" as the epidemic in Huangshi faded soon afterward. COVID-19 epidemic was characterized by mild cases in Huangshi, accounting for 82.66% of total cases. Moreover, 50 asymptomatic infections were identified in adults and children. In addition, we found confirmed cases in 19 familial clusters and 21 healthcare workers, supporting interhuman transmission.

CONCLUSIONS

Our study reported the temporal dynamics and characteristics of the COVID-19 epidemic in Huangshi city, China, across the unprecedented intervention. Such new epidemiological inference might provide further guidance on current lockdown measures in high-risk cities and, subsequently, help improve public health intervention strategies against the pandemic on the country and global levels.

摘要

背景

为控制 2019 年新型冠状病毒病(COVID-19)的传播,中国于 2020 年 1 月 23 日对武汉实施封城,并迅速将封锁范围扩大到湖北省的另外 12 个城市。我们旨在描述其中一个城市的流行病学特征,并强调当前实施的封锁和非药物干预措施的效果。

方法

我们从公开的疾病数据库中检索了黄石和武汉报告的病例数据。通过实地调查收集了黄石疑似或确诊病例的当地流行病学数据。用报告病例和观察病例的数据构建了流行曲线。

结果

截至 2020 年 3 月 27 日,黄石报告的累计确诊 COVID-19 病例和病死率分别为 1015 例和 3.74%,而武汉分别为 50006 例和 5.08%。1 月 24 日之后,基于黄石观察病例的流行曲线变得平坦。2020 年 2 月 1 日被确定为“转折点”,此后黄石的疫情很快消退。黄石的 COVID-19 疫情以轻症病例为特征,占总病例数的 82.66%。此外,还在成人和儿童中发现了 50 例无症状感染者。此外,我们还发现了 19 个家庭聚集性确诊病例和 21 例医护人员感染,支持人际传播。

结论

我们的研究报告了中国黄石市在前所未有的干预措施下 COVID-19 疫情的时间动态和特征。这种新的流行病学推断可能为当前高危城市的封锁措施提供进一步的指导,并随后有助于改善国家和全球层面的大流行公共卫生干预策略。

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