1,6-烯炔的时间经济型自由基级联环化/卤叠氮化反应：构建高官能化琥珀酰亚胺衍生物
Time-Economical Radical Cascade Cyclization/Haloazidation of 1,6-Enynes: Construction of Highly Functional Succinimide Derivatives.
作者信息
Gu Yan, Dai Lei, Mao Kaimin, Zhang Jinghang, Wang Chang, Zhao Liming, Rong Liangce
机构信息
School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, P.R. China.
出版信息
Org Lett. 2020 Apr 17;22(8):2956-2960. doi: 10.1021/acs.orglett.0c00682. Epub 2020 Apr 7.
PMID:32255346
Abstract
A "time-economical" radical cascade cyclization/haloazidation of 1,6-enynes provides a direct approach to access highly functional succinimide compounds. Moderate to excellent yields along with excellent / ratio were obtained under the reaction features of broad substrate scope, good functional group tolerance, and mild reaction conditions.
摘要
1,6-烯炔的“时间经济”自由基串联环化/卤叠氮化反应为获得高官能化琥珀酰亚胺化合物提供了一种直接方法。该反应具有底物范围广、官能团耐受性好、反应条件温和等特点，能以中等至优异的产率以及出色的 / 比例得到产物。
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