直接面向消费者的药品广告对公众胃食管反流病认知的影响：一项关于非处方质子泵抑制剂的研究
The Impact of Direct-to-Consumer Pharmaceutical Advertising on Public Knowledge of Gastroesophageal Reflux Disease: A Study on Over-the-Counter Proton Pump Inhibitors.
作者信息
AlShammari Maram, Assiri Ghadah, Bin Buraykan Mohammed, Almogbel Yasser, Arafah Azher, Bashatah Adel, AlRuthia Yazed
机构信息
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Department of Pharmacy Practice, College of Pharmacy, Qassim University, Buraidah, Saudi Arabia.
出版信息
Patient Prefer Adherence. 2020 Mar 20;14:635-642. doi: 10.2147/PPA.S245391. eCollection 2020.
BACKGROUND
The use of direct-to-consumer advertising (DTCA) to promote sales of over-the-counter (OTC) pharmaceuticals used to manage common medical conditions, such as gastroesophageal reflux disease (GERD), is increasing. However, the educational value of these advertisements as well as the public perceptions of this type of advertising remain largely unknown among non-English speaking populations.
OBJECTIVE
The aim of this study was to explore the public perceptions and educational value of a short motion graphic video documenting the lifestyle of person with GERD and presenting a brief introduction to the role of proton pump Inhibitors (PPIs) in relieving the symptoms.
METHODS
This was a prospective quasi-experimental study in which a short mock advertising motion graphic video was shown to a sample of adult individuals in malls and shopping centers in different cities across Saudi Arabia. Participants were required to express their levels of agreement with six statements concerning their perceptions of DTCA of OTC drugs, and answer a quiz consisting of three questions and enquiries about their knowledge of GERD and the OTC drugs used in its treatment.
RESULTS
Two hundred and ninety-five participants were involved in this study, the majority of whom were female (55.30%). After watching the video, the percentages of participants who strongly agreed or agreed that DTCA is a credible source of information and encourages them to purchase the marketed drug have increased significantly (<0.05). With regard to the quiz, the percentages of participants with correct answers regarding the definition of GERD, knowledge of OTC drugs for GERD, and awareness of the common side effects of PPIs increased from 81.69% to 95.93%, 69.83% to 96.27%, and 46.44% to 91.53%, respectively (<0.0001).
CONCLUSION
DTCA of OTC drugs for GERD, particularly if the content complies with the regulatory requirements, can promote the public knowledge of the disease and treatment options.
背景
利用面向消费者的广告（DTCA）来促进用于治疗常见病症（如胃食管反流病，GERD）的非处方药（OTC）的销售正在增加。然而，在非英语人群中，这些广告的教育价值以及公众对这类广告的看法在很大程度上仍不为人所知。
目的
本研究的目的是探讨一段简短的动态图形视频的公众看法和教育价值，该视频记录了GERD患者的生活方式，并简要介绍了质子泵抑制剂（PPI）在缓解症状方面的作用。
方法
这是一项前瞻性准实验研究，向沙特阿拉伯不同城市的商场和购物中心的成年个体样本展示了一段简短的模拟广告动态图形视频。参与者被要求对关于他们对OTC药物DTCA看法的六条陈述表达同意程度，并回答一个由三个问题组成的测验以及询问他们对GERD及其治疗中使用的OTC药物的了解情况。
结果
295名参与者参与了本研究，其中大多数为女性（55.30%）。观看视频后，强烈同意或同意DTCA是可靠信息来源并鼓励他们购买所售药物的参与者百分比显著增加（<0.05）。关于测验，对GERD定义、GERD的OTC药物知识以及PPI常见副作用知晓情况回答正确的参与者百分比分别从81.69%增至95.93%、69.83%增至96.27%以及46.44%增至91.53%（<0.0001）。
结论
用于GERD的OTC药物的DTCA，特别是如果内容符合监管要求，可以促进公众对该疾病和治疗选择的了解。
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