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[皮肤肿瘤炎性浸润细胞的免疫学及免疫细胞化学研究]

[Immunological and immunocytochemical studies of the inflammatory infiltrating cells of cutaneous tumors].

作者信息

Viac J, Schmitt D, Claudy A, Bustamante R, Perrot H, Thivolet J

出版信息

Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):109-10.

PMID:322573
Abstract

The identication of mononuclear cells extracted from various inflammatory infiltrates of cutaneous tumours has been investigated and the relative amount of B and T cells determinated according to various assays. It has been found that there were two different patterns of distribution of the cells in the infiltrates: one with a E/EAC ratio similar 5 (squamous and basalcell carcinomas), the other with a E/EAC ratio similar 1(malignant melanoma). The identification in situ of Ig-producing cells has been developed in the same tissues fixed in Bouin's solution. The relative frequency of these cells has been determinated and appears very low in the malignant melanoma.

摘要

对从皮肤肿瘤的各种炎性浸润中提取的单核细胞进行了鉴定,并根据各种检测方法测定了B细胞和T细胞的相对数量。已发现浸润中细胞存在两种不同的分布模式:一种E/EAC比值约为5(鳞状细胞癌和基底细胞癌),另一种E/EAC比值约为1(恶性黑色素瘤)。在固定于波因氏液的相同组织中开展了原位产生免疫球蛋白细胞的鉴定。已测定了这些细胞的相对频率,结果显示其在恶性黑色素瘤中非常低。

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