Alfath Zineb, Ferdjallah Asmaa, Greengard Emily, Askari Sabeen K, Sadak Karim T, Correll Colleen K
University of Minnesota Medical Center, Minneapolis, MN, United States.
Division of Pediatric Hematology & Oncology, University of Minnesota, Minneapolis, MN, United States.
Front Pediatr. 2020 Feb 28;8:77. doi: 10.3389/fped.2020.00077. eCollection 2020.
Henoch-Schönlein purpura (HSP) is a common systemic vasculitis affecting children. It is managed in the outpatient setting and rarely associated with malignancy. We present a case of neuroblastoma in a 7-year-old boy diagnosed after suspected HSP. Our case highlights the importance of maintaining a broad differential diagnosis in children with atypical HSP and performing a skin biopsy with immunofluorescence when a rash is present.
过敏性紫癜（HSP）是一种常见的影响儿童的系统性血管炎。它在门诊环境中进行治疗，很少与恶性肿瘤相关。我们报告一例7岁男孩在疑似患有HSP后被诊断为神经母细胞瘤的病例。我们的病例强调了对非典型HSP患儿保持广泛鉴别诊断的重要性，以及在出现皮疹时进行免疫荧光皮肤活检的重要性。
