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严重腹痛:过敏性紫癜皮疹出现前的非典型初始及主要症状。

Severe abdominal pain: an atypical initial and leading symptom preceding skin rash in Henoch-Schönlein purpura.

作者信息

Brozikova Hana, Barochova Libuse, Sykora Josef, Schwarz Jan, Lad Vaclav, Cvalinova Dominika, Greda Marek, Kutilek Stepan

机构信息

Department of Pediatrics, Klatovy Hospital, Klatovy, Czech Republic, Klatovy Hospital, Klatovy, Czech Republic.

Department of Pediatrics, Faculty Hospital and Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic.

出版信息

Sudan J Paediatr. 2022;22(2):179-184. doi: 10.24911/SJP.106-1576094862.

DOI:10.24911/SJP.106-1576094862
PMID:36875952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9983764/
Abstract

Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood and is clinically characterised by purpura, abdominal pain, arthritis and renal involvement. Scarcely, some patients with HSP may not always show visible rash and can present with insidious abdominal symptoms. We present two patients: an 8-year-old boy who was initially considered as having infectious diarrhoea and mesenteric lymphadenitis, then intussusception, appendicitis, appendicopathia oxyuriaca and post-operative ileus. However, he was finally diagnosed with HSP, as the typical rash appeared 10 days after onset of abdominal symptoms. The second patient was a 5-year-old boy with recurrent vomiting, abdominal pain and mild dehydration, where swollen joints and typical rash appeared on day 3. Both patients were successfully managed with orally administered corticosteroids. The patients did not have any further consequences of HSP.

摘要

过敏性紫癜(HSP)是儿童期最常见的血管炎,临床特征为紫癜、腹痛、关节炎和肾脏受累。少数情况下,一些HSP患者可能并不总是出现可见皮疹,而是表现为隐匿的腹部症状。我们报告两名患者:一名8岁男孩,最初被认为患有感染性腹泻和肠系膜淋巴结炎,随后又被诊断为肠套叠、阑尾炎、蛲虫性阑尾炎和术后肠梗阻。然而,最终他被诊断为HSP,因为典型皮疹在腹部症状出现10天后出现。第二名患者是一名5岁男孩,有反复呕吐、腹痛和轻度脱水症状,在第3天出现关节肿胀和典型皮疹。两名患者均通过口服糖皮质激素成功治疗。两名患者均未出现HSP的任何进一步后果。

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本文引用的文献

1
Atypical purpura location in a Sudanese infant with Henoch-Schönlein purpura.一名患有过敏性紫癜的苏丹婴儿出现非典型紫癜部位。
Sudan J Paediatr. 2021;21(2):186-189. doi: 10.24911/SJP.106-1614703471.
2
[Henoch-Schönlein Purpura Presenting as Intussusception].[以肠套叠形式表现的过敏性紫癜]
Korean J Gastroenterol. 2017 Jun 25;69(6):372-376. doi: 10.4166/kjg.2017.69.6.372.
3
Henoch-Schonlein purpura without typical lesions, presenting with gastrointestinal manifestations and kidney involvement following influenza - A case report.无典型皮损的过敏性紫癜,流感后出现胃肠道表现及肾脏受累—— 1例报告
J Pak Med Assoc. 2016 Oct;66(10):1339-1342.
4
[Abdominal symptoms necessitating surgical intervention as the initial presentation of Henoch-Schönlein purpura in children - case reports].[以腹部症状为首发表现且需手术干预的儿童过敏性紫癜——病例报告]
Pol Merkur Lekarski. 2016 Jun;40(240):377-9.
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Henoch-Schönlein without Purpura: A Case Report and Review Literature.无紫癜型过敏性紫癜:一例报告及文献复习
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HENOCH-SCHONLEIN PURPURA IN CHILDHOOD A FIFTEEN-YEAR EXPERIENCE AT A TERTIARY HOSPITAL.儿童过敏性紫癜:一家三级医院的十五年经验
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Henoch-Schönlein purpura complicated by acalculous cholecystitis and intussusception, and following recurrence with appendicitis.过敏性紫癜并发无结石性胆囊炎和肠套叠,且复发后伴阑尾炎。
Paediatr Int Child Health. 2016 May;36(2):157-9. doi: 10.1080/20469047.2015.1109250. Epub 2016 Jan 29.
8
[Clinical characteristics of Henoch-Schönlein purpura in children].[儿童过敏性紫癜的临床特征]
Zhongguo Dang Dai Er Ke Za Zhi. 2015 Oct;17(10):1079-83.
9
Penile Skin Involvement as the First Presentation of Henoch-Schonlein Purpura Report of Nine Cases and Review of Literature.以阴茎皮肤受累为首发表现的过敏性紫癜:9例报告并文献复习
Iran J Pediatr. 2015 Aug;25(4):e2177. doi: 10.5812/ijp.2177. Epub 2015 Aug 24.
10
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