三种放射治疗技术在左侧乳腺癌根治术后患者放疗中的剂量学比较。

Dosimetric Comparison of Three Radiotherapy Techniques in Irradiation of Left-Sided Breast Cancer Patients after Radical Mastectomy.

机构信息

Department of Radiation Oncology, Wuhan University, Renmin Hospital, Wuhan, 430060 Hubei Province, China.

Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079 Hubei Province, China.

出版信息

Biomed Res Int. 2020 Mar 26;2020:7131590. doi: 10.1155/2020/7131590. eCollection 2020.

RESULTS

The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (D) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for D of the heart and left ventricle ( < 0.05). A dose for left anterior descending artery from the three techniques had no significant difference. Compared with the 9FIMRT plans, the V (%) and V (%) for the ipsilateral lung were significantly reduced with TSP and VMAT ( < 0.05). The V (%) and V (%) for the ipsilateral lung turned out to be similar between VMAT and TSP techniques.

CONCLUSIONS

Our study indicates that VMAT should be a better choice of radiotherapy for left-sided breast cancer patients after radical mastectomy. If VMAT is unavailable, 9FIMRT can achieve better CI and HI values and be more MU-efficient compared with TSP; however, TSP can effectively reduce the low dose volume of the ipsilateral lungs and heart.

结果

VMAT 计划在靶区剂量适形指数（CI）、均匀性指数（HI）、同侧肺保护、机器跳数（MU）和对侧乳腺最大剂量（D）方面均优于 TSP 和 9FIMRT 计划。TSP 为心脏和左心室 D 提供了更好的保护（<0.05）。三种技术的左前降支 D 无显著差异。与 9FIMRT 计划相比，TSP 和 VMAT 显著降低了同侧肺的 V（%）和 V（%）（<0.05）。VMAT 和 TSP 技术之间的同侧肺 V（%）和 V（%）相似。