2019 年，在埃塞俄比亚西南部的吉马医疗中心，对接受随访的成年糖尿病患者中糖尿病足溃疡的流行情况及其相关因素进行了一项基于机构的横断面研究。
Prevalence of Diabetic Foot Ulcer and Associated Factors among Adult Diabetic Patients on Follow-Up Clinic at Jimma Medical Center, Southwest Ethiopia, 2019: An Institutional-Based Cross-Sectional Study.
机构信息
Department of Biomedical Sciences (Clinical Anatomy), College of Medical, Sciences, Institute of Health Sciences, Jimma University, Ethiopia.
Department of Biomedical Sciences (Medical Biochemistry), College of Medical, Sciences, Institute of Health Sciences, Jimma University, Ethiopia.
出版信息
J Diabetes Res. 2020 Mar 15;2020:4106383. doi: 10.1155/2020/4106383. eCollection 2020.
BACKGROUND
Diabetic foot ulceration is a devastating complication of diabetes mellitus and is a major source of morbidity and mortality. So far, there are few published data on diabetic foot ulcers and its determinants among diabetic patients on follow-up at Jimma Medical Center. Hence, the aim of this study was to assess the prevalence of diabetic foot ulcer and its determinants among patients with diabetes mellitus at Jimma Medical Center.
METHODS
A hospital-based cross-sectional study was conducted from June 1 to August 30, 2019, and systematic random sampling technique was applied. The total number of study subjects who participated in the study was 277. Data were collected using an interview-administered structured questionnaire. Data were entered into EpiData version 3.1 and exported to SPSS version 20 software for analysis. Analysis was done using descriptive statistics and logistic regression. A variable having a value of <0.25 in the bivariate model was subjected to multivariate analysis to avoid confounding the variable's effect. Adjusted odds ratios (AOR) were calculated at 95% confidence interval and considered significant with a value of <0.25 in the bivariate model was subjected to multivariate analysis to avoid confounding the variable's effect. Adjusted odds ratios (AOR) were calculated at 95% confidence interval and considered significant with a.
RESULT
The mean of age of participants was 50.1 ± 14.19 years. More than three-fourths of participants (82.7%) were type 2 DM. The mean duration of diabetic patients was 6.00 ± 5.07 years. The prevalence of diabetic foot ulcer was 11.6% among study participants. According to multivariate logistic regression analysis, previous history of ulceration (AOR = 5.77; 95% CI: 2.37, 14.0) and peripheral neuropathy (AOR = 11.2; 95% CI: 2.8, 44.4) were independent predictors of diabetic foot ulcer.
CONCLUSION
The prevalence of diabetic foot ulcer was 11.6%. Previous history of ulceration and peripheral neuropathy were associated with diabetic foot ulcer. The health care providers are recommended to thoroughly give emphasis during follow-up of patients who had previous history of ulceration and peripheral neuropathy in order to decrease the occurrence of diabetic foot ulcer.
背景
糖尿病足溃疡是糖尿病的一种严重并发症，是发病率和死亡率的主要来源。到目前为止，关于糖尿病患者在接受吉马医疗中心随访时的糖尿病足溃疡及其决定因素，发表的数据很少。因此，本研究旨在评估吉马医疗中心糖尿病患者中糖尿病足溃疡的患病率及其决定因素。
方法
这是一项 2019 年 6 月 1 日至 8 月 30 日进行的基于医院的横断面研究，采用系统随机抽样技术。参与研究的总人数为 277 人。使用访谈式结构化问卷收集数据。数据录入 EpiData 版本 3.1 并导出到 SPSS 版本 20 软件进行分析。使用描述性统计和逻辑回归进行分析。在双变量模型中 值<0.25 的变量进行多变量分析，以避免混淆变量的影响。计算调整后的优势比（AOR），置信区间为 95%，并认为在双变量模型中 值<0.25 的变量具有统计学意义。
结果
参与者的平均年龄为 50.1±14.19 岁。超过四分之三的参与者（82.7%）为 2 型糖尿病。糖尿病患者的平均病程为 6.00±5.07 年。研究参与者中糖尿病足溃疡的患病率为 11.6%。根据多变量逻辑回归分析，既往溃疡史（AOR=5.77；95%CI：2.37，14.0）和周围神经病变（AOR=11.2；95%CI：2.8，44.4）是糖尿病足溃疡的独立预测因素。
结论
糖尿病足溃疡的患病率为 11.6%。既往溃疡史和周围神经病变与糖尿病足溃疡有关。建议医疗保健提供者在对有既往溃疡史和周围神经病变的患者进行随访时，要彻底重视，以降低糖尿病足溃疡的发生。
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