甜蜜人生：葡萄糖在小鼠胚胎中指导细胞命运。
Living a Sweet Life: Glucose Instructs Cell Fate in the Mouse Embryo.
机构信息
Mammalian Embryo and Stem Cell Group, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Mammalian Embryo and Stem Cell Group, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK; Division of Biology and Biological Engineering, California Institute of Technology, 1200 E California Blvd, Pasadena, CA 91125, USA.
出版信息
Dev Cell. 2020 Apr 6;53(1):1-2. doi: 10.1016/j.devcel.2020.03.012.
It has long been known that glucose is required for the development of pre-implantation mouse embryos, but the mechanism accounting for such a requirement has remained unknown. In this issue of Developmental Cell, Chi et al. dissect the molecular pathways that respond to the state of glucose metabolism to drive the morula to blastocyst transition.
长期以来，人们都知道葡萄糖是胚胎着床前的小鼠胚胎发育所必需的，但导致这种需求的机制仍然未知。在本期《发育细胞》中，Chi 等人剖析了响应葡萄糖代谢状态的分子途径，以推动桑葚胚向囊胚的转变。
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