Canberk Sule, Tischler Verena, Engels Marianne
IPATIMUP, Institute of Molecular Pathology and Immunology of University of Porto, Porto, Portugal,
I3S, Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal,
Acta Cytol. 2020;64(5):463-470. doi: 10.1159/000506724. Epub 2020 Apr 7.
In June 2019, a lung symposium was held at the 42nd European Congress of Cytology in Malmö, Sweden. Due to the current importance of cytological samples in the diagnoses and molecular analysis to set up the utmost management of lung cancer patients, cytologists from different countries shared the experience of their institutions. The place of the cytological samples gains more and more importance on the potential long-term survival gain through personalized medicine and this harbors the improvement of the guidelines both in pathology and cytology field. In this symposium, the new 6-tiered reporting system for pulmonary cytology proposed by the Papanicolaou Society of Cytopathology and detailed cytomorphological approach to lung carcinoma including lookalike lesions and DNA- and RNA-based analysis of cytology material have been discussed. The cytopathologist plays a pivotal role in ensuring success of a correct triage for the cytology material to be sure of the adequacy and quality of the yield from the rapid on-site evaluation till the report which should encompass molecular profile in rational patient management.
2019年6月，一场肺部专题研讨会在瑞典马尔默举行的第42届欧洲细胞学大会上召开。鉴于目前细胞学样本在肺癌患者的诊断及分子分析以制定最佳治疗方案方面的重要性，来自不同国家的细胞学家分享了各自机构的经验。通过个性化医疗，细胞学样本对于潜在的长期生存获益愈发重要，这推动了病理学和细胞学领域指南的改进。在本次研讨会上，对细胞病理学帕潘icolaou学会提出的新的六级肺部细胞学报告系统，以及肺癌详细的细胞形态学方法（包括相似病变）和基于细胞学材料的DNA及RNA分析进行了讨论。细胞病理学家在确保对细胞学材料进行正确分类的成功方面发挥着关键作用，以确保从快速现场评估到报告（报告应涵盖合理患者管理中的分子特征）所获得的样本产量的充分性和质量。
