Muthumalage Thivanka, Friedman Michelle R, McGraw Matthew D, Ginsberg Garry, Friedman Alan E, Rahman Irfan
Department of Environmental Medicine, University of Rochester Medical Center Box 850, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Department of Chemistry & Biochemistry, The College of Brockport, State University of New York, Brockport, NY 14420, USA.
Toxics. 2020 Apr 3;8(2):25. doi: 10.3390/toxics8020025.
The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths. We have identified chemical constituents in e-cig counterfeit cartridges and compared these to medical-grade and CBD containing cartridges. Apart from vitamin E acetate (VEA) and tetrahydrocannabinol (THC), other potential toxicants were identified including solvent-derived hydrocarbons, silicon conjugated compounds, various terpenes, pesticides/plasticizers/polycaprolactones, and metals. This study provides additional insights into the chemicals associated with EVALI cartridges and thus may contribute to the underlying disease mechanism of acute lung injury.
美国疾病控制中心宣布，由于急诊室入院率和死亡率居高不下，电子烟或雾化产品使用相关肺损伤（EVALI）已成为全国性疫情。我们已确定了电子烟假冒烟弹中的化学成分，并将其与医用级和含CBD的烟弹进行了比较。除了醋酸维生素E（VEA）和四氢大麻酚（THC）外，还鉴定出了其他潜在毒物，包括溶剂衍生的碳氢化合物、硅共轭化合物、各种萜类化合物、农药/增塑剂/聚己内酯以及金属。这项研究为与EVALI烟弹相关的化学物质提供了更多见解，因此可能有助于了解急性肺损伤的潜在发病机制。
