Research Group on Gene-Environment Interactions and Health (GIIGAS), Instituto de Biomedicina (IBIOMED), University of León, 24071 León, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
Nutrients. 2020 Apr 3;12(4):996. doi: 10.3390/nu12040996.
: Traditional anthropometrics such as body mass index (BMI) or waist circumference (WC) do not fully capture the complex biology of body fat (BF) in the elderly. The Clinica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index, based on BMI, is proposed as a better indicator of BF. However, its relation with BMI is not clear. The aim was to compare the agreement between CUN-BAE, BMI, and WC in those aged ≥50 years. : A cross-sectional sample of 3153 Caucasian healthy adults was taken from the MCC-Spain study. The Pearson's correlation and its 95% confidence interval (CI), adiposity distribution, and Kappa Index (95%CI) were calculated. : The correlation of CUN-BAE with WC is 0.18 (95%CI 0.14-0.21) and that with BMI is moderate (r 0.58; 95%CI 0.55-0.60), but both increased strongly by sex. Agreement (normal weight/overweight/obesity) of CUN-BAE with BMI is 7% and with WC is 18%. : The correlation and the degree of agreement of CUN-BAE with BMI and WC are low in individuals aged over 50, but it is higher by sex. Thus, this different criterion of obesity may have clinical applications. More studies with a gold standard are needed to evaluate the CUN-BAE in elderly adults.
传统的人体测量学指标,如体重指数(BMI)或腰围(WC),并不能完全反映老年人体脂肪(BF)的复杂生物学特性。基于 BMI 的 Clinica Universidad de Navarra-Body Adiposity Estimator(CUN-BAE)指数被提议作为 BF 的更好指标。然而,其与 BMI 的关系尚不清楚。本研究旨在比较 CUN-BAE、BMI 和 WC 在≥50 岁人群中的一致性。
本研究采用横断面样本,来自 MCC-Spain 研究的 3153 名白种健康成年人。计算了 Pearson 相关系数及其 95%置信区间(CI)、肥胖分布和 Kappa 指数(95%CI)。
CUN-BAE 与 WC 的相关性为 0.18(95%CI 0.14-0.21),与 BMI 的相关性为中度(r 0.58;95%CI 0.55-0.60),但在性别之间均显著增加。CUN-BAE 与 BMI 的一致性(正常体重/超重/肥胖)为 7%,与 WC 的一致性为 18%。
在 50 岁以上的个体中,CUN-BAE 与 BMI 和 WC 的相关性和一致性均较低,但在性别之间更高。因此,这种不同的肥胖标准可能具有临床应用价值。需要更多的金标准研究来评估 CUN-BAE 在老年人群中的应用。