Castagnola V, Cookman J, de Araújo J M, Polo E, Cai Q, Silveira C P, Krpetić Ž, Yan Y, Boselli L, Dawson K A
Centre for BioNano Interactions, School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland.
Nanoscale Horiz. 2017 Jul 1;2(4):187-198. doi: 10.1039/c6nh00219f. Epub 2017 Apr 13.
The range of possible nanostructures is so large and continuously growing, that collating and unifying the knowledge connected to them, including their biological activity, is a major challenge. Here we discuss a concept that is based on the connection of microscopic features of the nanomaterials to their biological impacts. We also consider what would be necessary to identify the features that control their biological interactions, and make them resemble each other in a biological context.
可能的纳米结构范围如此之广且不断扩大，以至于整理和统一与它们相关的知识，包括它们的生物活性，是一项重大挑战。在此，我们讨论一种基于纳米材料微观特征与其生物影响之间联系的概念。我们还思考确定控制其生物相互作用并使其在生物学环境中彼此相似的特征需要哪些条件。
