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基于蛋白质的材料:从来源到用于生物医学应用的创新可持续材料

Protein-based materials: from sources to innovative sustainable materials for biomedical applications.

作者信息

Silva Nuno H C S, Vilela Carla, Marrucho Isabel M, Freire Carmen S R, Pascoal Neto Carlos, Silvestre Armando J D

机构信息

CICECO and Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.

出版信息

J Mater Chem B. 2014 Jun 28;2(24):3715-3740. doi: 10.1039/c4tb00168k. Epub 2014 May 8.

Abstract

Proteins display an essential role in numerous natural systems due to their structural and biological properties. Given their unique properties, proteins have been thoroughly investigated in the last few decades, offering a myriad of solutions for the development of innovative biomaterials, including films, foams, composites and gels, in particular for biomedical applications such as drug delivery systems, biosensors and scaffolds for tissue regeneration. In this context, this review intends to give a general overview of the potential of protein based materials within the sustainable polymers context, covering aspects ranging from protein types, selection/isolation to properties of protein based (nano)materials and biomedical applications, passing through preparation methodologies of materials.

摘要

由于蛋白质的结构和生物学特性,它们在众多自然系统中发挥着至关重要的作用。鉴于其独特的性质,在过去几十年中对蛋白质进行了深入研究,为创新生物材料的开发提供了无数解决方案,包括薄膜、泡沫、复合材料和凝胶,特别是用于生物医学应用,如药物递送系统、生物传感器和组织再生支架。在此背景下,本综述旨在对可持续聚合物背景下基于蛋白质的材料的潜力进行概述,涵盖从蛋白质类型、选择/分离到基于蛋白质的(纳米)材料的性质和生物医学应用等方面,还包括材料的制备方法。

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