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用于生物医学应用的电纺材料中的农工植物蛋白

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application.

作者信息

Zdraveva Emilija, Gaurina Srček Višnja, Kraljić Klara, Škevin Dubravka, Slivac Igor, Obranović Marko

机构信息

Faculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28, 10000 Zagreb, Croatia.

Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.

出版信息

Polymers (Basel). 2023 Jun 14;15(12):2684. doi: 10.3390/polym15122684.

Abstract

Plant proteins are receiving a lot of attention due to their abundance in nature, customizable properties, biodegradability, biocompatibility, and bioactivity. As a result of global sustainability concerns, the availability of novel plant protein sources is rapidly growing, while the extensively studied ones are derived from byproducts of major agro-industrial crops. Owing to their beneficial properties, a significant effort is being made to investigate plant proteins' application in biomedicine, such as making fibrous materials for wound healing, controlled drug release, and tissue regeneration. Electrospinning technology is a versatile platform for creating nanofibrous materials fabricated from biopolymers that can be modified and functionalized for various purposes. This review focuses on recent advancements and promising directions for further research of an electrospun plant protein-based system. The article highlights examples of zein, soy, and wheat proteins to illustrate their electrospinning feasibility and biomedical potential. Similar assessments with proteins from less-represented plant sources, such as canola, pea, taro, and amaranth, are also described.

摘要

植物蛋白因其在自然界中的丰富性、可定制性、生物降解性、生物相容性和生物活性而备受关注。由于全球对可持续性的关注,新型植物蛋白来源的可用性正在迅速增加,而广泛研究的植物蛋白则来自主要农业工业作物的副产品。由于其有益特性,人们正在大力研究植物蛋白在生物医学中的应用,例如制造用于伤口愈合、控制药物释放和组织再生的纤维材料。静电纺丝技术是一个多功能平台,可用于制造由生物聚合物制成的纳米纤维材料,这些材料可针对各种目的进行改性和功能化。本综述重点关注基于静电纺丝植物蛋白系统的最新进展和未来研究的有前景方向。文章突出了玉米醇溶蛋白、大豆蛋白和小麦蛋白的例子,以说明它们的静电纺丝可行性和生物医学潜力。还描述了对来自代表性较低的植物来源(如油菜籽、豌豆、芋头和苋菜)的蛋白质的类似评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/10301402/25ade709a3d0/polymers-15-02684-g001.jpg

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