Obiweluozor Francis O, GhavamiNejad Amin, Maharjan Bikendra, Kim Jinwoo, Park Chan Hee, Kim Cheol Sang
Department of Bionanosystem Engineering, Graduate School, Chonbuk National University, Jeonju 561-756, Republic of Korea.
J Mater Chem B. 2017 Jul 21;5(27):5373-5379. doi: 10.1039/c7tb00539c. Epub 2017 Jun 23.
We engineered a novel shape memory polymer (SMP), a nanocomposite hydrogel containing polydopamine nanospheres (PDNs) as a self-expandable tubular hydrogel under near-infrared (NIR) irradiation. When NIR is applied to the nanocomposite hydrogel, the PDN nanoparticles absorb light, which is locally dissipated as heat to become the driving force for shape transition behavior. Since the fabricated PDN material has good mechanical properties, including rapid self-expandability and good biocompatibility, when developed with good heating properties under (NIR) irradiation, it might be useful for many biomedical applications such as the treatment of coronary artery disease.
我们设计了一种新型形状记忆聚合物（SMP），即一种包含聚多巴胺纳米球（PDN）的纳米复合水凝胶，它在近红外（NIR）照射下可作为一种自膨胀管状水凝胶。当对纳米复合水凝胶施加近红外光时，聚多巴胺纳米球颗粒吸收光线，并将其局部耗散为热量，从而成为形状转变行为的驱动力。由于所制备的聚多巴胺纳米球材料具有良好的机械性能，包括快速自膨胀性和良好的生物相容性，且在近红外照射下具有良好的加热性能，因此它可能在许多生物医学应用中发挥作用，如冠状动脉疾病的治疗。
