Popov Piotr, Mann Elizabeth K, Jákli Antal
Department of Physics, Kent State University, Kent, OH 44242, USA.
J Mater Chem B. 2017 Jul 14;5(26):5061-5078. doi: 10.1039/c7tb00809k. Epub 2017 May 30.
We briefly review studies of liquid crystal films suspended in submillimeter size grids for biosensing applications and beyond. Due to intense recent research, the sensitivity of liquid crystal films to targeted biologically relevant agents can be increased, and the LC surface can be functionalized to be sensitive only to pre-assigned pathogens. Beyond sensor applications, we show that novel liquid crystal defect structures can be used to manipulate separation and deposition of lipids. Finally, we demonstrate that not only the nematic liquid crystal phase, but also chiral nematic (cholesteric and blue phase) and smectic liquid crystals can be used for sensing and may extend the sensitivity and/or the selection of biomaterials, which can be sensed.
我们简要回顾了悬浮在亚毫米尺寸网格中的液晶薄膜在生物传感及其他应用方面的研究。由于近期的大量研究,液晶薄膜对靶向生物相关试剂的灵敏度得以提高,并且液晶表面可以进行功能化处理,使其仅对预先指定的病原体敏感。除了传感器应用,我们还展示了新型液晶缺陷结构可用于操控脂质的分离和沉积。最后,我们证明不仅向列相液晶,而且手性向列相(胆甾相和蓝相)以及近晶相液晶都可用于传感,并且可能扩展可被传感的生物材料的灵敏度和/或选择范围。