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大量样本中拔毛癖的精神病理学相关性及其与健康相关生活质量的关联。

Trichotillomania-psychopathological correlates and associations with health-related quality of life in a large sample.

机构信息

Unichristus Medical School, Fortaleza, Brazil.

Division of Dermatology, Women's College Hospital, Toronto, Ontario, Canada.

出版信息

CNS Spectr. 2021 Jun;26(3):282-289. doi: 10.1017/S109285292000111X. Epub 2020 Apr 8.

Abstract

BACKGROUND

Relatively few studies have assessed the prevalence, correlates, and independent impact on quality of life (QoL) of trichotillomania (TTM) in large samples.

METHODS

Consecutive participants (N = 7639) were recruited from a cross-sectional web-based study. Sociodemographic data were collected and several validated self-reported mental health measures were completed (Minnesota Impulsive Disorders Interview, Hypomania checklist, Fagerström Test for Nicotine Dependence, Alcohol Use Disorders Identification Test, Early Trauma Inventory Self Report-Short Form, and the Symptom Checklist-90-Revised Inventory). Health-related QoL was assessed with the World Health Organization QoL abbreviated scale (WHOQOL-Bref). Multivariable models adjusted associations to potential confounders.

RESULTS

The sample was predominantly composed of young females (71.3%; mean age: 27.2 ± 7.9 years). The prevalence of probable TTM was 1.4% (95% confidence intervals [CI]: 1.2-1.7), and was more common among females. Participants with probable TTM had a greater likelihood of having co-occurring probable depression (adjusted odds ratio [ORadj] = 1.744; 95% CI: 1.187-2.560), tobacco (ORadj = 2.250; 95% CI: 1.191-4.250), and alcohol (ORadj = 1.751; 95% CI: 1.169-2.621) use disorders. Probable TTM was also independently associated with suicidal ideation (ORadj = 1.917; 95% CI: 1.224-3.003) and exposure to childhood sexual abuse (ORadj = 1.221; 95% CI: 1.098-1.358). In addition, a positive screen for TTM had more impaired physical and mental QoL.

CONCLUSIONS

TTM was associated with a positive screen for several psychiatric comorbidities as well as impaired physical and psychological QoL. Efforts towards the recognition and treatment of TTM across psycho-dermatology services are warranted.

摘要

背景

在大规模样本中,评估拔毛癖(TTM)的患病率、相关因素以及对生活质量(QoL)的独立影响的研究相对较少。

方法

连续招募了来自横断面网络研究的 7639 名参与者。收集了社会人口统计学数据,并完成了几项经过验证的自我报告心理健康测量(明尼苏达冲动障碍访谈、躁狂检查表、尼古丁依赖 Fagerström 测试、酒精使用障碍识别测试、早期创伤清单自我报告简短版和症状清单-90 修订版库存)。使用世界卫生组织生活质量简表(WHOQOL-Bref)评估健康相关生活质量。多变量模型调整了与潜在混杂因素的关联。

结果

该样本主要由年轻女性(71.3%;平均年龄:27.2 ± 7.9 岁)组成。可能 TTM 的患病率为 1.4%(95%置信区间[CI]:1.2-1.7),在女性中更为常见。患有可能 TTM 的参与者更有可能同时患有可能的抑郁症(调整后的优势比[ORadj] = 1.744;95% CI:1.187-2.560)、烟草(ORadj = 2.250;95% CI:1.191-4.250)和酒精(ORadj = 1.751;95% CI:1.169-2.621)使用障碍。可能的 TTM 也与自杀意念(ORadj = 1.917;95% CI:1.224-3.003)和儿童期性虐待(ORadj = 1.221;95% CI:1.098-1.358)呈独立相关。此外,TTM 的筛查呈阳性与身体和精神生活质量受损有关。值得在心理皮肤病学服务中努力识别和治疗 TTM。

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