Unichristus Medical School, Fortaleza, Brazil.
Division of Dermatology, Women's College Hospital, Toronto, Ontario, Canada.
CNS Spectr. 2021 Jun;26(3):282-289. doi: 10.1017/S109285292000111X. Epub 2020 Apr 8.
Relatively few studies have assessed the prevalence, correlates, and independent impact on quality of life (QoL) of trichotillomania (TTM) in large samples.
Consecutive participants (N = 7639) were recruited from a cross-sectional web-based study. Sociodemographic data were collected and several validated self-reported mental health measures were completed (Minnesota Impulsive Disorders Interview, Hypomania checklist, Fagerström Test for Nicotine Dependence, Alcohol Use Disorders Identification Test, Early Trauma Inventory Self Report-Short Form, and the Symptom Checklist-90-Revised Inventory). Health-related QoL was assessed with the World Health Organization QoL abbreviated scale (WHOQOL-Bref). Multivariable models adjusted associations to potential confounders.
The sample was predominantly composed of young females (71.3%; mean age: 27.2 ± 7.9 years). The prevalence of probable TTM was 1.4% (95% confidence intervals [CI]: 1.2-1.7), and was more common among females. Participants with probable TTM had a greater likelihood of having co-occurring probable depression (adjusted odds ratio [ORadj] = 1.744; 95% CI: 1.187-2.560), tobacco (ORadj = 2.250; 95% CI: 1.191-4.250), and alcohol (ORadj = 1.751; 95% CI: 1.169-2.621) use disorders. Probable TTM was also independently associated with suicidal ideation (ORadj = 1.917; 95% CI: 1.224-3.003) and exposure to childhood sexual abuse (ORadj = 1.221; 95% CI: 1.098-1.358). In addition, a positive screen for TTM had more impaired physical and mental QoL.
TTM was associated with a positive screen for several psychiatric comorbidities as well as impaired physical and psychological QoL. Efforts towards the recognition and treatment of TTM across psycho-dermatology services are warranted.
在大规模样本中,评估拔毛癖(TTM)的患病率、相关因素以及对生活质量(QoL)的独立影响的研究相对较少。
连续招募了来自横断面网络研究的 7639 名参与者。收集了社会人口统计学数据,并完成了几项经过验证的自我报告心理健康测量(明尼苏达冲动障碍访谈、躁狂检查表、尼古丁依赖 Fagerström 测试、酒精使用障碍识别测试、早期创伤清单自我报告简短版和症状清单-90 修订版库存)。使用世界卫生组织生活质量简表(WHOQOL-Bref)评估健康相关生活质量。多变量模型调整了与潜在混杂因素的关联。
该样本主要由年轻女性(71.3%;平均年龄:27.2 ± 7.9 岁)组成。可能 TTM 的患病率为 1.4%(95%置信区间[CI]:1.2-1.7),在女性中更为常见。患有可能 TTM 的参与者更有可能同时患有可能的抑郁症(调整后的优势比[ORadj] = 1.744;95% CI:1.187-2.560)、烟草(ORadj = 2.250;95% CI:1.191-4.250)和酒精(ORadj = 1.751;95% CI:1.169-2.621)使用障碍。可能的 TTM 也与自杀意念(ORadj = 1.917;95% CI:1.224-3.003)和儿童期性虐待(ORadj = 1.221;95% CI:1.098-1.358)呈独立相关。此外,TTM 的筛查呈阳性与身体和精神生活质量受损有关。值得在心理皮肤病学服务中努力识别和治疗 TTM。