Yoon Y H, Marmor M F
Department of Ophthalmology, Stanford University School of Medicine, CA 94305.
Ophthalmology. 1988 Oct;95(10):1385-8. doi: 10.1016/s0161-6420(88)33000-9.
To determine how quickly laser photocoagulation produces a bond between retina and pigment epithelium, the authors measured the strength of retinal adhesion after making laser burns through intact and recently reattached rabbit retina. After photocoagulation of intact retina, the adhesive force was reduced 50% at 8 hours but increased beyond normal (to approximately 140%) by 24 hours and remained twice normal between 3 days and 4 weeks. Photocoagulation of retina that had just settled after experimental detachment produced similar results, except that the maximum strength of adhesion (reached at 2 weeks) was three times normal. In contrast, retina that reattached spontaneously, without photocoagulation, showed only 10% of normal adhesiveness at 24 hours, and still was only 75% of normal after 4 weeks. These data suggest that laser photocoagulation may be acutely beneficial in the prevention or management of retinal tears and detachments.
为了确定激光光凝术能多快地在视网膜和色素上皮之间形成粘连，作者通过完整的和近期复位的兔视网膜进行激光烧灼后，测量了视网膜粘连的强度。对完整视网膜进行光凝后，8小时时粘合力降低了50%，但到24小时时增加至超过正常水平（约为140%），并在3天至4周之间维持在正常水平的两倍。对实验性脱离后刚刚复位的视网膜进行光凝产生了类似的结果，只是粘连的最大强度（在2周时达到）是正常水平的三倍。相比之下，未经光凝自发复位的视网膜在24小时时仅显示出正常粘附性的10%，4周后仍仅为正常水平的75%。这些数据表明，激光光凝术在预防或处理视网膜裂孔和脱离方面可能具有即时益处。
