Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Acta Ophthalmol. 2022 Dec;100(8):e1600-e1605. doi: 10.1111/aos.15144. Epub 2022 Mar 29.
To compare the treatment success of air with fluorinated gas (20% SF or 14% C F ) tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment.
A retrospective cohort study comprised of 1023 consecutive primary retinal detachment cases between 2014 and 2020. We employed a univariate multivariable binary logistic regression model.
We used intraocular gas tamponades in 872 cases with PVR grade B or lower: air tamponade was used in 414 eyes and 458 eyes were treated with a type of fluorinated gas tamponade. There was no significant difference in the type of tamponade with regard to the re-detachment rate (95% CI -1.0% and 4.1%). Additionally, also in the subgroup of rhegmatogenous retinal detachments with inferior located retinal defects we found no significant difference between the two types of tamponade (p = 0.54 Fisher's exact). The multivariable model, which included tamponade, PVR grade, a retinal detachment involving the 6 o'clock position and age as covariates, also showed no significant effect of tamponade choice on treatment success (OR 0.5, 95% 0.2-1.0, p = 0.10).
We found no difference in treatment success with air tamponade versus fluorinated gas tamponades in the repair of primary retinal detachments, this also includes inferiorly located retinal tears and detachments.
比较经平坦部玻璃体切除术治疗原发性孔源性视网膜脱离时，空气与含氟气体（20%SF6 或 14%C2F6）填充的治疗成功率。
本回顾性队列研究纳入了 2014 年至 2020 年间的 1023 例连续原发性视网膜脱离病例。我们采用单变量多变量二项逻辑回归模型。
我们在 872 例 PVR 分级 B 或更低的病例中使用了眼内气体填充：414 只眼使用了空气填充，458 只眼使用了含氟气体填充。在再脱离率方面，两种填充方式没有显著差异（95%CI-1.0%和 4.1%）。此外，在下方视网膜裂孔的孔源性视网膜脱离亚组中，我们也发现两种填充方式之间没有显著差异（p=0.54 Fisher 确切概率法）。包括填充、PVR 分级、6 点钟位置的视网膜脱离以及年龄作为协变量的多变量模型也表明，填充方式的选择对治疗成功率没有显著影响（OR 0.5，95%0.2-1.0，p=0.10）。
我们发现，在修复原发性视网膜脱离时，空气填充与含氟气体填充的治疗成功率没有差异，这包括下方视网膜裂孔和脱离。
