J Refract Surg. 2020 Apr 1;36(4):214-222. doi: 10.3928/1081597X-20200212-01.
To evaluate and compare the objective and subjective outcomes between bilateral implantation of the extended depth of focus (EDOF) Mini Well intraocular lens (IOL) and the aspheric monofocal Mini-4-Ready IOL (both SIFI S.p.A., Catania, Italy).
This prospective comparative study included 25 patients (50 eyes) bilaterally implanted with an EDOF Mini Well IOL (EDOF group) and 25 patients (50 eyes) bilaterally implanted with a Mini-4-Ready IOL (monofocal group). Three-month follow-up data included corrected and uncorrected distance visual acuity at 4 m and 80, 67, and 40 cm. Defocus curves, subjective and objective contrast sensitivity, and objective optical quality (modulation transfer function cutoff and Strehl ratio calculated with Optical Quality Analysis System [OQAS]; Visiometrics SL, Terrassa, Spain), halometry, and reading performance were measured. Subjective visual quality was evaluated based on National Eye Institute Refractive Error Quality of Life Instrument 42 (NEI RQL-42) scores.
Postoperative uncorrected and corrected monocular and binocular intermediate and near visual acuity was significantly better in the EDOF group (P < .001). No differences were observed for distance visual acuity (P ⩾ .312). Defocus curve outcomes for myopic values were better in the EDOF group (P < .001). No significant differences were found in hyperopic (obtained in steps of +0.50 diopters [D] from emmetropia to 1.50 D) values (P ⩾ .095), contrast sensitivity curves (P ⩾ .087), or OQAS outcomes (P ⩾ .138). Halometric values were significantly better in the monofocal group (P < .05). There was a correlation between mean keratometry values and intermediate/near visual acuity. Significantly better NEI RQL-42 subscale scores for near vision, far vision, activity limitations, glare, dependence on correction, and suboptimal correction were noted in the EDOF group (P < .05).
Intermediate and near visual acuity was better after EDOF IOL than after aspheric monofocal IOL implantation while maintaining similar levels of visual quality, except for halo perception. [J Refract Surg. 2020;36(4):214-222.].
评估并比较扩展景深（EDOF）Mini Well 人工晶状体（IOL）双侧植入与非球面单焦点 Mini-4-Ready IOL（均来自 SIFI S.p.A.，意大利卡塔尼亚）的客观和主观结果。
本前瞻性对照研究纳入了 25 名患者（50 只眼），他们分别接受了 EDOF Mini Well IOL（EDOF 组）和 Mini-4-Ready IOL（单焦点组）双侧植入。3 个月的随访数据包括 4 m 和 80、67、40 cm 处的矫正和未矫正远视力。测量离焦曲线、主观和客观对比敏感度以及客观光学质量（调制传递函数截止值和斯特列尔比，采用光学质量分析系统[OQAS]计算；Visiometrics SL，西班牙特拉萨）、眼压计和阅读性能。基于国家眼科研究所屈光不正生活质量量表 42（NEI RQL-42）评分评估主观视觉质量。
EDOF 组术后单眼和双眼的未矫正和矫正中间和近视力明显更好（P<.001）。远视力无差异（P≥.312）。EDOF 组近视值的离焦曲线结果更好（P<.001）。在远视值（从正视开始以+0.50 屈光度[D]逐渐增加到 1.50 D）方面无显著差异（P≥.095），对比敏感度曲线（P≥.087）或 OQAS 结果（P≥.138）无差异。眼压计值在单焦点组显著更好（P<.05）。平均角膜曲率值与中间/近视力存在相关性。EDOF 组在近视力、远视力、活动受限、眩光、对矫正的依赖以及矫正不足方面的 NEI RQL-42 子量表评分显著更高（P<.05）。
EDOF IOL 植入后的中间和近视力优于非球面单焦点 IOL 植入，同时保持相似的视觉质量水平，除了光晕感知。
