Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Cell Metab. 2020 Apr 7;31(4):662-663. doi: 10.1016/j.cmet.2020.03.016.
Covalent cysteine modification by reactive oxygen species (ROS) has been implicated in regulating diverse biological processes, yet global understanding of this modification has remained fragmentary. Developing new approaches for detecting cysteine modification, Xiao et al. (2020) recently charted a comprehensive map of cysteine oxidation across tissues and life stages.
活性氧（ROS）引起的半胱氨酸的共价修饰与多种生物过程的调节有关，但人们对半胱氨酸修饰的整体认识仍然是零散的。为了开发检测半胱氨酸修饰的新方法，Xiao 等人（2020 年）最近绘制了一张横跨组织和生命阶段的半胱氨酸氧化的综合图谱。
