Winkelmann R K, Carapeto F J, Jordon R E
Br J Dermatol. 1977 Mar;96(3):231-8. doi: 10.1111/j.1365-2133.1977.tb06130.x.
Immunofluorescent study of the skin of nine patients with mesenchymal, inflammatory scleroderma (mixed connective tissue disease) revealed immunoglobulin and complement deposition at the basement membrane or within blood vessel walls. The skin specimens of ten patients with systemic scleroderma were negative for immunofluorescence. It is proposed that basement membrane or vascular (or both) immunofluorescence is an excellent means of identifying the infrequent patient who has scleroderma and myositis or lupus erythematosus in whom a corticosteroid response may occur.
对9例间质性炎性硬皮病（混合性结缔组织病）患者的皮肤进行免疫荧光研究，结果显示免疫球蛋白和补体沉积于基底膜或血管壁内。10例系统性硬皮病患者的皮肤标本免疫荧光检查呈阴性。有人提出，基底膜或血管（或两者）免疫荧光检查是识别罕见的合并硬皮病和肌炎或红斑狼疮且可能对皮质类固醇有反应的患者的极佳方法。
