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1
Author Correction: Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model.作者更正：缺氧诱导因子（HIF）脯氨酰羟化酶抑制剂诱导自噬并在体外缺血模型中具有保护作用。
Sci Rep. 2020 Apr 8;10(1):6041. doi: 10.1038/s41598-020-63108-2.
2
Application of in-vitro screening methods on hypoxia inducible factor prolyl hydroxylase inhibitors.体外筛选方法在缺氧诱导因子脯氨酰羟化酶抑制剂中的应用。
Bioorg Med Chem. 2017 Aug 1;25(15):3891-3899. doi: 10.1016/j.bmc.2017.05.026. Epub 2017 May 13.
3
Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.补体 C1q 由胶原蛋白脯氨酰 4 羟化酶羟化，并且对稳定缺氧诱导因子的脯氨酰羟化酶结构域抑制剂的非靶标抑制敏感。
Kidney Int. 2017 Oct;92(4):900-908. doi: 10.1016/j.kint.2017.03.008. Epub 2017 May 12.
4
The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.脯氨酰羟化酶抑制对肾缺血的保护作用需要在缺血前应用，但优于 EPO 治疗。
Nephrol Dial Transplant. 2012 Mar;27(3):929-36. doi: 10.1093/ndt/gfr379. Epub 2011 Jul 8.
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Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model.脯氨酰羟化酶抑制剂激活缺氧诱导转录因子可降低小鼠主动脉同种异体移植模型中移植动脉硬化的水平。
Interact Cardiovasc Thorac Surg. 2016 May;22(5):561-70. doi: 10.1093/icvts/ivv352. Epub 2016 Jan 27.
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Hypoxia-inducible factor prolyl 4-hydroxylase inhibition in cardiometabolic diseases.缺氧诱导因子脯氨酰4-羟化酶抑制在心脏代谢疾病中的作用
Pharmacol Res. 2016 Dec;114:265-273. doi: 10.1016/j.phrs.2016.11.003. Epub 2016 Nov 8.
7
miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning.在延迟性缺血预处理中，微小RNA-21通过靶向脯氨酰羟化酶结构域蛋白2发挥肾脏保护作用。
Nephrology (Carlton). 2017 May;22(5):366-373. doi: 10.1111/nep.12787.
8
Investigational hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHI) for the treatment of anemia associated with chronic kidney disease.研究用缺氧诱导因子脯氨酰羟化酶抑制剂（HIF-PHI）治疗与慢性肾脏病相关的贫血。
Expert Opin Investig Drugs. 2018 Jul;27(7):613-621. doi: 10.1080/13543784.2018.1493455. Epub 2018 Jul 12.
9
Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?缺氧诱导因子 (HIF) 羟化酶介导的蛋白质羟化：独特还是普遍存在？
Cells. 2019 Apr 26;8(5):384. doi: 10.3390/cells8050384.
10
Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.硒蛋白2通过AMPK介导的脯氨酰羟化酶调节来抑制缺氧诱导因子-1α的积累。
Free Radic Biol Med. 2016 Dec;101:511-523. doi: 10.1016/j.freeradbiomed.2016.11.014. Epub 2016 Nov 11.

引用本文的文献

1
Prolyl hydroxylase domain inhibitor is an effective pre-hospital pharmaceutical intervention for trauma and hemorrhagic shock.脯氨酰羟化酶结构域抑制剂是创伤和失血性休克有效的院前药物干预手段。
Sci Rep. 2024 Feb 16;14(1):3874. doi: 10.1038/s41598-024-53945-w.
2
Renal Cellular Autophagy in Obesity: Boon or Bane?肥胖症中的肾脏细胞自噬：是福还是祸？
Semin Nephrol. 2021 Jul;41(4):349-357. doi: 10.1016/j.semnephrol.2021.06.006.

作者更正：缺氧诱导因子（HIF）脯氨酰羟化酶抑制剂诱导自噬并在体外缺血模型中具有保护作用。

Author Correction: Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model.

作者信息

Singh Ayesha, Wilson James W, Schofield Christopher J, Chen Ruoli

机构信息

Institute for Science and Technology in Medicine, School of Pharmacy, Keele University, Newcastle under Lyme, Staffordshire, ST5 5BG, United Kingdom.

Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, OX1 5JJ, United Kingdom.

出版信息

Sci Rep. 2020 Apr 8;10(1):6041. doi: 10.1038/s41598-020-63108-2.

DOI:10.1038/s41598-020-63108-2
PMID:32269283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7142094/
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

摘要

本文的一个修订版本已发表，可通过本文顶部的链接获取。