Su Hui, Sun Haitao, Xie Yuanzhong, Gong Weiyun, Shi Hao
Department of Medical Imaging, Shandong Provincial Qianfoshan Hospital, Shandong University Jinan 250012, Shandong, China.
Department of Medical Imaging, Taian City Central Hospital Taian 271000, Shandong, China.
Int J Clin Exp Pathol. 2020 Mar 1;13(3):509-514. eCollection 2020.
Most of the studies on hippocampal sulcal cavities (HSCs) have been focused on the hippocampal lesions, lacking of systemic investigations on the normal individuals. In this study, we aimed to investigate the detection rate and number of HSCs together with the correlation between HSCs and the gender, sides, hippocampal volume, and age. In total, 187 healthy subjects underwent 3.0 Tesla magnetic resonance scan. Chi square test was utilized for the comparison of HSCs detection rate among the male and female individuals. Student's t-test was used to compare the HSCs number between the subjects with different ages as well as different body sides. Analysis of variance was performed for the comparison of primary hippocampal volume, corrected hippocampal volume, and age. Person regression analysis was utilized to analyze the correlation between HSCs number and the primary hippocampal volume, corrected hippocampal volume, and age. The incidence of HSCs was 95% among the 187 subjects. There was no significant gender difference in the incidence of HSCs (=0.448). There was no statistically significant difference in the number of HSCs on the left and right sides (=0.093). There were statistically significant differences in mean age between groups (<0.01). Pearson correlation analysis was performed on HSCs with age, hippocampal original volume and corrected volume, and the correlation coefficients were 0.316, -0.005 and 0.055. Healthy population has a high HSCs incidence, which had no significant gender-related difference. There is no significant difference of HSCs number between the left and right sides. HSCs showed a low correlation with age and no correlation with hippocampal volume.
大多数关于海马沟腔（HSCs）的研究都集中在海马病变上，缺乏对正常个体的系统性研究。在本研究中，我们旨在调查HSCs的检出率和数量，以及HSCs与性别、左右侧、海马体积和年龄之间的相关性。总共187名健康受试者接受了3.0特斯拉磁共振扫描。采用卡方检验比较男性和女性个体之间HSCs的检出率。采用Student's t检验比较不同年龄和不同身体侧别受试者之间的HSCs数量。进行方差分析以比较初级海马体积、校正海马体积和年龄。采用Person回归分析来分析HSCs数量与初级海马体积、校正海马体积和年龄之间的相关性。187名受试者中HSCs的发生率为95%。HSCs的发生率在性别上无显著差异（=0.448）。左右两侧HSCs的数量无统计学显著差异（=0.093）。各组之间的平均年龄有统计学显著差异（<0.01）。对HSCs与年龄、海马原始体积和校正体积进行Pearson相关分析，相关系数分别为0.316、-0.005和0.055。健康人群中HSCs的发生率较高，且无显著的性别相关差异。左右两侧HSCs的数量无显著差异。HSCs与年龄的相关性较低，与海马体积无相关性。
