Xie Xu-Ting, Zhang Xiao, Liu Yang, Chen Xian-Qiang, Cheong Kit-Leong
1Guangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Institute of Marine Sciences, Shantou University, Shantou, 515063 Guangdong People's Republic of China.
2Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, 530200 Guangxi People's Republic of China.
3 Biotech. 2020 Apr;10(4):189. doi: 10.1007/s13205-020-02175-8. Epub 2020 Apr 2.
This study determined the composition of the monosaccharide, 3, 6-anhydrogalactose (AnGal), in red algae and explored the potential whitening activity of the extract. Using gas chromatography-mass spectrometry (GC-MS), the AnGal composition of six different species of red seaweed (, , , , , and ) was successfully analyzed, revealing molar ratios ranging from 1.0:1.0 to 1.0:3.1 of AnGal and galactose (Gal), respectively. Employing the tyrosinase inhibition assay, the skin-whitening effect of AnGal red seaweed polysaccharides was determined. Polysaccharides from , , and as well as their degradation products showed higher tyrosinase inhibitory activity (inhibition rates 24.2-26.8%). These results suggest that the GC-MS approach could conveniently be used in quality control or for the quantitative determination of AnGal and Gal in red seaweed polysaccharides as well as exploring their potential application in cosmetic and functional food products. The findings here exhibited that red seaweed polysaccharides and their degradation products were potential ingredients for cosmeceutical industries.
本研究测定了红藻中3,6 - 脱水半乳糖（AnGal）这一单糖的组成，并探究了提取物的潜在美白活性。使用气相色谱 - 质谱联用仪（GC - MS），成功分析了六种不同红藻（、、、、、和）的AnGal组成，结果显示AnGal与半乳糖（Gal）的摩尔比分别为1.0:1.0至1.0:3.1。采用酪氨酸酶抑制试验，测定了AnGal红藻多糖的皮肤美白效果。来自、、和的多糖及其降解产物表现出较高的酪氨酸酶抑制活性（抑制率为24.2 - 26.8%）。这些结果表明，GC - MS方法可方便地用于红藻多糖中AnGal和Gal的质量控制或定量测定，以及探索它们在化妆品和功能性食品中的潜在应用。此处的研究结果表明，红藻多糖及其降解产物是药妆行业的潜在成分。
