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联合加速角膜胶原交联和基质内Kerarings植入治疗晚期圆锥角膜。

Combined accelerated corneal collagen crosslinking and intrastromal Kerarings implantation for treatment of advanced superior keratoconus.

作者信息

Mounir Amr, Mostafa Engy Mohamed

机构信息

Sohag Faculty of Medicine, Ophthalmology Department, Sohag University, Sohag, Egypt.

出版信息

GMS Ophthalmol Cases. 2020 Feb 27;10:Doc10. doi: 10.3205/oc000137. eCollection 2020.

DOI:10.3205/oc000137
PMID:32269908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7113618/
Abstract

To report early results of combined accelerated corneal collagen crosslinking (CXL) and intrastromal Kerarings implantation by femtosecond laser in a case of advanced superior keratoconus. The patient was a 27-year-old male with left eye grade 3 keratoconus with superior cone. He was diagnosed by Sirius Scheimpflug corneal topography (CSO, Florence, Italy). The right eye had previously been subjected to penetrating keratoplasty. The uncorrected visual acuity (UCVA) in the right eye (RE) was 1.2 LogMAR, best corrected visual acuity (BCVA) was 0.8 by a refraction of -7.50Ds -3.00Dc @12. The UCVA in the left eye (LE) was 1.2 LogMAR, BCVA was 0.9 by a refraction of -8.50 Ds -5.50Dc @169. Intrastromal Kerarings implantation by femtosecond laser was carried out by IntraLase (iFS, Abbott) along with accelerated transepithelial corneal collagen crosslinking by KXL system (Avedro, USA) in the same session. Follow-up was done for a period of 12 months after surgery. The patient was followed up for 12 months with improvement of visual acuity as regards UCVA and BCVA and improvement of corneal topographic parameters including keratometry and front and back elevations. Combined accelerated corneal collagen crosslinking and intrastromal Kerarings implantation by femtosecond laser is an effective method in the treatment of this uncommon type of keratoconus.

摘要

报告飞秒激光联合加速角膜胶原交联(CXL)和基质内角膜环植入术治疗晚期上方圆锥角膜的早期结果。患者为27岁男性,左眼为3级上方圆锥角膜。通过Sirius眼前节分析系统(CSO,意大利佛罗伦萨)诊断。右眼此前已接受穿透性角膜移植术。右眼未矫正视力(UCVA)为1.2 LogMAR,最佳矫正视力(BCVA)为0.8,验光结果为-7.50Ds -3.00Dc @12。左眼UCVA为1.2 LogMAR,BCVA为0.9,验光结果为-8.50 Ds -5.50Dc @169。在同一次手术中,使用IntraLase(iFS,雅培)进行飞秒激光基质内角膜环植入术,并使用KXL系统(美国Avedro)进行加速上皮下角膜胶原交联。术后随访12个月。对患者进行了12个月的随访,结果显示UCVA和BCVA的视力有所改善,角膜地形图参数包括角膜曲率测量以及前后表面高度也有所改善。飞秒激光联合加速角膜胶原交联和基质内角膜环植入术是治疗这种罕见类型圆锥角膜的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/7113618/22d6ba174dc7/OC-10-10-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/7113618/529965c18479/OC-10-10-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/7113618/22d6ba174dc7/OC-10-10-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/7113618/529965c18479/OC-10-10-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75aa/7113618/22d6ba174dc7/OC-10-10-g-002.jpg

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本文引用的文献

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Sequential Keraring implantation and corneal cross-linking for the treatment of keratoconus in children with vernal keratoconjunctivitis.序贯式角膜基质环植入术联合角膜交联术治疗患有春季角结膜炎的儿童圆锥角膜
Clin Ophthalmol. 2017 Oct 24;11:1891-1895. doi: 10.2147/OPTH.S150022. eCollection 2017.
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