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银屑病关节炎疾病影响问卷:有效性、可靠性及其临床潜力。

Psoriatic arthritis impact of disease questionnaire: validity, reliability and its clinical potential.

机构信息

Department of Physical Medicine and Rehabilitation, Ankara City Hospital, Üniversiteler Mah. 1604. Cad. Çankaya, Ankara, Turkey.

Department of Physical Medicine and Rehabilitaton, Division of Rheumatology, Ankara University, Faculty of Medicine, Ankara, Turkey.

出版信息

Rheumatol Int. 2020 Jun;40(6):959-967. doi: 10.1007/s00296-020-04575-8. Epub 2020 Apr 8.

Abstract

The psoriatic arthritis impact of disease (PSAID) questionnaire has been developed to measure disease impact on patients with psoriatic arthritis. It was aimed to evaluate its validity and reliability in association with sociodemographic and clinical factors and compare it with disease activity and patient-reported outcome measures in a Turkish psoriatic arthritis population. A prospective observational study was conducted to validate the Turkish version of the PSAID. All consecutive patients with psoriatic arthritis were evaluated between January 2019 and October 2019. Demographic and clinical features were recorded. The PSAID and patient-reported outcome measures were applied to all patients. Interclass and intra-class correlation analyses were performed. Convergent validity and correlation coefficients were used for validity analyses. There were 80 patients with a mean age of 50.2 ± 9.9 years. Cronbach's α value of the PSAID and intra-class correlation were 0.799 and 0.984, respectively. The total median PSAID score was 4.7. Pain, fatigue, ability to work, functional capacity and feeling of discomfort were the five highest-scoring subscales. There was satisfactory internal consistency for each subscale of the PSAID. As disease severity increased from low to high, the PSAID scores significantly increased. There were acceptable correlations between the PSAID and other patient-reported outcome measures. The PSAID is shown to be a reliable and valid questionnaire in Turkish patients with psoriatic arthritis. Good correlation with disease activity and patient-reported outcome measures represent an opportunity to use the PSAID in clinical practice to tailor individualized treatment choices.

摘要

银屑病关节炎疾病影响(PSAID)问卷旨在测量银屑病关节炎患者的疾病影响。本研究旨在评估其在与社会人口统计学和临床因素相关联的有效性和可靠性,并将其与土耳其银屑病关节炎人群中的疾病活动度和患者报告的结局测量进行比较。进行了一项前瞻性观察性研究,以验证 PSAID 的土耳其版本。2019 年 1 月至 2019 年 10 月期间,对所有连续的银屑病关节炎患者进行了评估。记录了人口统计学和临床特征。所有患者均接受了 PSAID 和患者报告的结局测量。进行了组内和组间相关性分析。使用效标关联和相关系数进行了有效性分析。共有 80 例患者,平均年龄为 50.2±9.9 岁。PSAID 的 Cronbach's α 值和组内相关系数分别为 0.799 和 0.984。PSAID 的总分中位数为 4.7。疼痛、疲劳、工作能力、功能能力和不适感觉是得分最高的五个子量表。PSAID 的每个子量表都具有令人满意的内部一致性。随着疾病严重程度从低到高,PSAID 评分显著增加。PSAID 与其他患者报告的结局测量之间存在可接受的相关性。PSAID 显示在土耳其银屑病关节炎患者中是一种可靠且有效的问卷。与疾病活动度和患者报告的结局测量具有良好的相关性,为在临床实践中使用 PSAID 来定制个体化的治疗选择提供了机会。

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