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越南老年心血管病住院患者发生肌少症风险的初步研究。

A preliminary study to identify the likely risk for sarcopenia in older hospitalised patients with cardiovascular disease in Vietnam.

机构信息

Department of Geriatrics and Gerontology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.

Department of Interventional Cardiology, Thong Nhat Hospital, Ho Chi Minh City, Vietnam.

出版信息

Australas J Ageing. 2020 Sep;39(3):e315-e321. doi: 10.1111/ajag.12789. Epub 2020 Apr 8.

Abstract

OBJECTIVE

To investigate the prevalence of sarcopenia, its associated factors and its impact on readmission in older hospitalised patients with cardiovascular diseases (CVD) in Vietnam.

METHODS

Patients aged ≥60 with CVD were recruited from 12/2018 to 6/2019 at a tertiary hospital in Vietnam. Sarcopenia was defined by the criteria proposed by the Asian Working Group for Sarcopenia (AWGS).

RESULTS

There were 251 participants, with a mean age of 73.7 ± 8.8, 39.4% were female, and 34.3% had sarcopenia. On multivariable logistic regression, heart failure, chronic kidney disease and being currently unmarried were significantly associated with sarcopenia. The incidence of 5-month readmission was 35.7% (50.0% in sarcopenic participants and 27.9% in non-sarcopenic participants, P = .001). Sarcopenia independently increased the risk of readmission (adjusted OR 2.19, 95% CI 1.08-4.42).

CONCLUSION

Sarcopenia was present in one-third of older hospitalised patients with CVD and increased their risk of readmission. This finding suggests the need to raise awareness of sarcopenia among clinicians and older patients in Vietnam.

摘要

目的

调查越南老年心血管疾病(CVD)住院患者中肌少症的流行情况、相关因素及其对再入院的影响。

方法

2018 年 12 月至 2019 年 6 月,在越南一家三级医院招募年龄≥60 岁且患有 CVD 的患者。肌少症的定义采用亚洲肌少症工作组(AWGS)提出的标准。

结果

共有 251 名参与者,平均年龄为 73.7±8.8 岁,39.4%为女性,34.3%存在肌少症。多变量逻辑回归分析显示,心力衰竭、慢性肾脏病和目前未婚与肌少症显著相关。5 个月时的再入院率为 35.7%(肌少症组为 50.0%,非肌少症组为 27.9%,P=0.001)。肌少症独立增加了再入院的风险(调整后的 OR 2.19,95%CI 1.08-4.42)。

结论

三分之一的老年 CVD 住院患者存在肌少症,增加了再入院的风险。这一发现表明,越南的临床医生和老年患者需要提高对肌少症的认识。

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