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胸骨伤口并发症:负压伤口治疗常规使用的结果

Sternal Wound Complications: Results of Routine Use of Negative Pressure Wound Therapy.

作者信息

Martino Andrea De, Re Federico Del, Falcetta Giosuè, Morganti Riccardo, Ravenni Giacomo, Bortolotti Uberto

机构信息

University Hospital Section of Cardiac Surgery Pisa Italy Section of Cardiac Surgery, University Hospital, Pisa, Italy.

University Hospital Section of Statistics Pisa Italy Section of Statistics, University Hospital, Pisa, Italy.

出版信息

Braz J Cardiovasc Surg. 2020 Feb 1;35(1):50-57. doi: 10.21470/1678-9741-2019-0242.

DOI:10.21470/1678-9741-2019-0242
PMID:32270960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7089751/
Abstract

INTRODUCTION

Negative pressure wound therapy (NPWT) has significantly improved outcomes in individuals with superficial and deep sternal wound dehiscence (SWD). We report our experience with NPWT to evaluate factors influencing effectiveness, duration of treatment and postoperative hospital stay.

METHODS

We reviewed 92 patients with postoperative SWD following a median sternotomy. Patients were divided into 2 groups: those with a superficial SWD (Group 1; 72, 78%) and those with a deep SWD (Group 2; 20, 28%). Group 1 was further divided into 3 subgroups based on NPWT duration.

RESULTS

In both groups, none of the preoperative characteristics examined showed a significant association with longer NPWT duration. In Group 2, there was a trend for postoperative bleeding and neurological complications to be associated with longer treatment duration. In the entire series, staph infection resulted a weak predictor of NPWT duration. In each Group 1 subgroup and in Group 2, treatment days were compared with duration of hospitalization until discharge. Mean post-NPWT hospital stay was 6 days in subgroup 1, 12 days in subgroup 2 and 20 days in subgroup 3 (P<0.0001). At a median 3-year follow-up, there were 4 late deaths, none related to wound complications. No cases of SWD recurrence were observed.

CONCLUSION

Our results confirm the effectiveness of NPWT in SWD management, while excessive treatment duration might have a negative impact on the length of hospital stay. Further studies are needed to define an optimal use of NPWT protocol.

摘要

引言

负压伤口治疗(NPWT)显著改善了表浅和深部胸骨伤口裂开(SWD)患者的治疗效果。我们报告了我们使用NPWT的经验,以评估影响其有效性、治疗持续时间和术后住院时间的因素。

方法

我们回顾了92例正中开胸术后发生SWD的患者。患者分为两组:表浅SWD患者(第1组;72例,78%)和深部SWD患者(第2组;20例,28%)。第1组根据NPWT持续时间进一步分为3个亚组。

结果

在两组中,所检查的术前特征均未显示与更长的NPWT持续时间有显著关联。在第2组中,术后出血和神经并发症有与更长治疗持续时间相关的趋势。在整个系列中,葡萄球菌感染是NPWT持续时间的一个弱预测因素。在第1组的每个亚组和第2组中,比较了治疗天数与出院前的住院时间。NPWT后的平均住院时间在亚组1中为6天,在亚组2中为12天,在亚组3中为20天(P<0.0001)。在中位3年随访时,有4例晚期死亡,均与伤口并发症无关。未观察到SWD复发病例。

结论

我们的结果证实了NPWT在SWD管理中的有效性,而过长的治疗持续时间可能会对住院时间产生负面影响。需要进一步研究来确定NPWT方案的最佳使用方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/4b6f3111a3d8/rbccv-35-01-0050-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/8a011caa018b/rbccv-35-01-0050-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/083d259622c3/rbccv-35-01-0050-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/4b6f3111a3d8/rbccv-35-01-0050-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/8a011caa018b/rbccv-35-01-0050-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/083d259622c3/rbccv-35-01-0050-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/7089751/4b6f3111a3d8/rbccv-35-01-0050-g03.jpg

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