Department of Vitreo-Retina, Aravind Eye Hospital, Madurai, India.
Department of Microbiology, Aravind Eye Hospital, Madurai, India.
Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1530-1536. doi: 10.1080/09273948.2020.1737143. Epub 2020 Apr 10.
: To describe the clinical and microbiological features, management outcomes, and prognostic factors of visual improvement in post-cataract surgery fungal endophthalmitis.: We evaluated 17 patients with culture-confirmed fungal endophthalmitis following cataract surgery. Data were collected regarding intravitreal antibiotics and antifungals, pars plana vitrectomy (PPV), intraocular lens (IOL) explantation, and scleral-fixated IOL (SFIOL) implantation. Clinical outcomes were recorded in terms of visual acuity and management strategies.: PPV was performed as a primary procedure at first presentation in three eyes. Fourteen eyes (82.3%) received intravitreal voriconazole. IOL explantation was performed in four eyes, followed by an SFIOL implantation in three eyes. Six eyes additionally presented with keratitis. At the final follow-up, cases having visual acuity ≥6/60 doubled from 17.6% to 35.3%. Eyes receiving antifungals had a trend toward worse visual outcome.: Corneal involvement in addition to endophthalmitis and the presence of were found to be poor prognostic markers.
: 描述白内障手术后真菌性眼内炎的临床和微生物学特征、治疗结果和预后因素：我们评估了 17 例经培养证实的白内障手术后真菌性眼内炎患者。收集了关于玻璃体内抗生素和抗真菌药物、玻璃体切除术（PPV）、眼内晶状体（IOL）取出术和巩膜固定型 IOL（SFIOL）植入术的数据。以视力和治疗策略记录临床结果。: 在首次就诊时，有 3 只眼作为主要手术进行了 PPV。14 只眼（82.3%）接受了玻璃体内伏立康唑治疗。4 只眼行 IOL 取出术，随后 3 只眼行 SFIOL 植入术。6 只眼另外出现了角膜炎。在最终随访时，视力≥6/60 的病例比例从 17.6%增加到 35.3%。接受抗真菌药物治疗的眼视力预后较差。: 除眼内炎外，还发现角膜受累和存在 是预后不良的标志物。
