[电子艾灸对遗忘型轻度认知障碍患者记忆功能的影响]
[Effect of electronic moxibustion on memory function in patients with amnestic mild cognitive impairment].
作者信息
Liu Qi-Qi, Chen Shang-Jie, Shen Guo-Ming, Jia Xin-Yan, Qiao Xiao-di, Wu Guo-Long
机构信息
Graduate School, Anhui University of CM, Hefei 230038, China; Department of Rehabilitation Medicine, Shenzhen Baoan Hospital Affiliated to Southern Medical University, Shenzhen 518101, Guangdong Province.
Graduate School, Anhui University of CM, Hefei 230038, China.
出版信息
Zhongguo Zhen Jiu. 2020 Apr 12;40(4):352-6. doi: 10.13703/j.0255-2930.20190608-k0002.
OBJECTIVE
To observe the effect of electronic moxibustion on memory function in the patients with amnestic mild cognitive impairment (aMCI).
METHODS
A total of 59 aMCI patients were randomized into an electronic moxibustion group (30 cases) and a placebo moxibustion group (29 cases). In the electronic moxibustion group, the electronic moxibustion was applied to Baihui (GV 20), Dazhui (GV 14), Mingmen (GV 4) and Taixi (KI 3), 45 ℃ in temperature, 20 min each time. The treatment was given once a day, 5 times a week. The treatment for 4 weeks was as one course and 2 courses were required totally. In the placebo moxibustion group, the moxa-free patch was used, 38 ℃ in temperature. The acupoint selection and the treatment frequency were same as the electronic moxibustion group. Before and after treatment, Rivermead behavior memory test (RBMT) was adopted to evaluate the global memory function of the patients in the two groups and the N-back task test was adopted to evaluate working memory function separately. Additionally, the mini-mental state examination (MMSE) and its immediate memory, Montreal cognitive assessment (MoCA) and its delay recall were adopted to evaluate the global cognitive function and memory function
RESULTS
In the electronic moxibustion group, after treatment, RBMT score, N-back accuracy rates, MMSE and MoCA scores and the scores of immediate memory and delay recall were improved significantly as compared with those before treatment (<0.01). In the placebo moxibustion group, the accuracy rates of 1-back and 2-back task and the scores of immediate memory and delay recall were improved obviously as compared with those before treatment (<0.05, <0.01). After treatment, the improvements of RBMT score, the accuracy rates of N-back task and MMSE and MoCA scores in the electronic moxibustion group were higher than those in the placebo moxibustion group (<0.05).
CONCLUSION
Electronic moxibustion improves memory function in the patients with amnestic mild cognitive impairment.
目的
观察电子艾灸对遗忘型轻度认知障碍（aMCI）患者记忆功能的影响。
方法
将59例aMCI患者随机分为电子艾灸组（30例）和假艾灸组（29例）。电子艾灸组采用电子艾灸百会（GV 20）、大椎（GV 14）、命门（GV 4）和太溪（KI 3），温度45℃，每次20分钟。每天治疗1次，每周5次。4周治疗为1个疗程，共需2个疗程。假艾灸组采用无艾片贴，温度38℃。穴位选择和治疗频率与电子艾灸组相同。治疗前后，采用Rivermead行为记忆测试（RBMT）评估两组患者的整体记忆功能，采用N-back任务测试分别评估工作记忆功能。此外，采用简易精神状态检查表（MMSE）及其即刻记忆、蒙特利尔认知评估量表（MoCA）及其延迟回忆评估整体认知功能和记忆功能。
结果
电子艾灸组治疗后，RBMT评分、N-back准确率、MMSE和MoCA评分以及即刻记忆和延迟回忆评分均较治疗前显著提高（<0.01）。假艾灸组1-back和2-back任务准确率以及即刻记忆和延迟回忆评分较治疗前明显提高（<0.05，<0.01）。治疗后，电子艾灸组RBMT评分、N-back任务准确率、MMSE和MoCA评分的改善程度高于假艾灸组（<0.05）。
结论
电子艾灸可改善遗忘型轻度认知障碍患者的记忆功能。
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